Sort   by:  
 Page size 
ProteomicsMapping viral protease-mediated processing of astrovirus nonstructural polyprotein C4PR_LIV
Many viruses with compact RNA genomes use a replication strategy involving the translation and proteolytic processing of a polyprotein. Astroviruses include a range of human and animal species and can infect cells of intestinal and neuronal origin. These viruses have positive-sense RNA genomes and t...
ORGANISM(S): Human astrovirus 1 Homo sapiens (Human) Human astrovirus MLB2 
2026-06-07 | PXD058484 | Pride
Tmt-hunter N-terminomics Astrovirus 
ProteomicsCLIPPER 2.0: Peptide level annotation and data analysis for positional proteomics
Positional proteomics methodologies have transformed protease research and have brought mass spectrometry (MS)-based degradomics studies to the forefront of protease characterization and system-wide interrogation of protease signaling. Considerable advancements in sensitivity and throughput of liqui...
ORGANISM(S): Homo sapiens (Human) 
2024-05-02 | PXD047261 | Pride
Lc-ms Post-translational modification Positional proteomics Computational proteomics Degradomics 
ProteomicsDoxycycline alters porcine renal proteome and degradome during hypothermic machine perfusion
Ischemia/reperfusion injury (IRI) is a hallmark of tissue injury in donation after circulatory death (DCD) kidneys. The implementation of hypothermic machine perfusion (HMP) provides a platform for repair of DCD kidneys. Doxycycline administration has shown protective effects during IRI. Here, we ex...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-08-12 | PXD029599 | Pride
Renal transplantation  ischemia/reperfusion injury  machine perfusion  proteomics 
ProteomicsPathological meprin a activity associated with degradation of dermokine drives a psoriasis-like skin phenotype in a novel genetic mouse model
Keratinocyte proliferation and differentiation is regulated via proteolytic networks. Dysregulation of proteases within these systems can cause hyperproliferative and inflammatory skin disorders. In healthy skin the metalloprotease meprin α is localized in the stratum basale, yet in wound healing ti...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-03 | PXD063928 | Pride
Degradomics Dia Mouse Psoriasis Tails Dermokine 
ProteomicsUnraveling the proteomic landscape of red-fleshed apples to identify regulators of anthocyanin accumulation
Anthocyanins are colorful plant pigments with antioxidant properties, and a diet rich in these flavonoids bears health benefits. Therefore, a strong anthocyanin accumulation in edible plant parts is of significant interest, and in Malus domestica, the domesticated apple, certain red-fleshed apple va...
ORGANISM(S): Malus domestica 
2025-06-06 | PXD062840 | Pride
Mal d proteins Malus domestica Acyltransferase Myb transcription factors Fruits 
Sort   by:  
 Page size