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TranscriptomicsMolecular consequences of Dlx3 deletion in mouse enamel organ as determined by RNASeq analysis
DLX3 is a homeodomain transcription factor involved in ameloblast differentiation and enamel formation. Mutations in DLX3 in human lead to defects in enamel. However, the downstream targets of Dlx3 transcriptional activity in the enamel organ have not been identified yet. In this study, we compared ...
ORGANISM(S): Mus musculus 
2015-05-14 | E-GEOD-57984 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse incisor tooth germ to associate changes in levels of mRNAs with development of enamel structure
The tooth is a convenient experimental model for the study of the basic mechanisms of organ development, including differentiation, cellular interaction, morphogenesis, and production and mineralization of extracellular matrices. The rodent incisor teeth grow continuously and exhibit all stages of t...
ORGANISM(S): Mus musculus 
2010-10-01 | E-MTAB-149 | biostudies-arrayexpress
ProteomicsSex determination of human remains from peptides in tooth enamel
Biological sex determination of human remains by means of a minimally destructive surface acid etch of tooth enamel and subsequent identification of sex chromosome linked isoforms of Amelogenin– an enamel-forming protein - by nano-liquid chromatography mass spectrometry(nanoLC-MS).
ORGANISM(S): Homo sapiens (Human) 
2017-12-12 | PXD007856 | Pride
Human Tooth enamel Lc-ms/ms 
ProteomicsSex estimation of human remains using the results of tooth enamel peptidomic analyses, LC-MSMS
Sex of individuals, estimated on human remains, is important information in anthropological, archaeological and forensic researches. In forensic anthropology, this is one of the key points for identifying a person. In archeology and paleoanthropology, information about sex is important for reconstru...
ORGANISM(S): Homo sapiens (Human) 
2020-06-24 | PXD017965 | Pride
Amelogenins Lc-msms Sex estimation Peptides Tooth enamel 
TranscriptomicsTranscription profiling of tooth germs from mouse fetuses and embryos
Study of changes in gene expression in mouse tooth germs between E15.5 and 21.5dpc
ORGANISM(S): Mus musculus 
2007-04-01 | E-MEXP-947 | biostudies-arrayexpress
TranscriptomicsNext-generation sequencing facilitates quantitative analysis of wild type and Bmp4f/f;Wnt1Cre tooth mesenchyme transcriptomes
Previous studies have suggested that Bmp4 is a key Msx1-dependent mesenchymal odontogenic signal for driving tooth morphogenesis through the bud-to-cap transition. Whereas the bud stage tooth developmental arrest in Msx1-/- mutant mice was accompanied by reduction in mesenchymal Bmp4 mRNA expression...
ORGANISM(S): Mus musculus 
2013-01-22 | E-GEOD-39918 | biostudies-arrayexpress
ProteomicsPig Tooth Pixelation - Tooth enamel forms in an ephemeral protein matrix where changes in protein abundance, composition and post-translational modifications are critical to achieve healthy enamel properties
Tooth enamel forms in an ephemeral protein matrix where changes in protein abundance, composition and post-translational modifications are critical to achieve healthy enamel properties. Amelogenin (AMELX) with its splice variants is the most abundant enamel matrix protein, with only one known phosph...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2019-07-19 | PXD013604 | Pride
Tooth Proteome Pig 
TranscriptomicsTranscription profiling of first molar tooth germ in PPAR-alpha knock-out and wild type mice
Embryologically the tooth is derived from both the ectoderm and neural crest (ectomesenchyme). It is often used as a model to study how epithelial–mesenchymal interactions can control differentiation and morphogenesis. During early development organs of ectodermal origin share both a set of signalli...
ORGANISM(S): Mus musculus 
2009-08-06 | E-MTAB-42 | biostudies-arrayexpress
ProteomicsAncient tooth enamel proteomes to help understand post mortem protein degradation over millions of years
The tooth enamel proteome is enzymatically broken down during development, which leads to a heterogenous distribution of remaining peptides of a protein sequence in a grown individual's enamelome. After death of the organism, the heterogeneous distribution of remaining peptides may be enhanced, as t...
ORGANISM(S): Equidae Proboscidea <placentals> 
2025-05-06 | PXD048972 | Pride
Proboscidea Paleoproteomics Equidae Ancient Enamel 
ProteomicsSex estimation of a Neanderthal tooth fragment using a minimally destructive acid-etch method for dimorphic enamel peptide analysis
Using a minimally destructive acid-etch procedure, this study successfully identified sex from a Neanderthal tooth fragment (c. 90,100-92,000 years old).
ORGANISM(S): Homo sapiens (Human) 
2024-05-24 | PXD038154 | Pride
Tooth enamel Sex estimation Amelogenin Neanderthal 
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