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ProteomicsAcetylome analysis of acetylation providing new insight into sclerotial generation in medicinal fungus Polyporus umbellatus
Polyporus umbellatus sclerotia are medicinal tissue, but little is known about acetylome of sclerotia generated from hyphae. Acetylated peptides in P. umbellatus were enriched by anti-acetyl-lysine antibody beaded agarose and DDA data were acquired by AB Triple TOF 5600+. Raw data were analyzed by P...
ORGANISM(S): Polyporus umbellatus GSX09 
2022-05-20 | PXD031195 | Pride
Ab triple tof5600+ Polyporus umbellatus 
ProteomicsCompatibility of distinct label-free proteomic workflows in absolute quantification of proteins linked to the oocyte quality in human follicular fluid (the Triple-Quad TOF workflow)
We present a comprehensive analysis of human follicular fluid proteome by comparing several strategies of sample preparation, mass spectrometry analysis, and data processing, resulting in the identification of 1638 proteins. We devised two separate label-free quantitative workflows, termed after the...
ORGANISM(S): Homo sapiens (Human) 
2021-07-23 | PXD024223 | Pride
Lc-ms/ms Oocyte quality control Human follicular fluid Oocyte maturity Total protein approach Swath-ms Proteome Blastocyst development 
MetabolomicsBacteroides uniformis degrades β-glucan to promote Lactobacillus johnsonii improving indole-3-lactic acid levels in alleviating colitis

The gut microbiota plays a crucial role in the onset and progression of inflammatory bowel disease (IBD). β-glucan (BG), a soluble dietary fiber widely present in oats, barley, fungi, yeast and some bacteria, has multiple bioactive properties such as mitigating intestinal inflammation; however, t...

2024-02-12 | MTBLS8950 | MetaboLights
MetabolomicsKidney protective effect of fermented celery polysaccharides and Eubacterium rectale in diabetic rats

This study aimed to investigate the protective effects of non-fermented celery polysaccharides (NFCP), fermented celery polysaccharides (FCP), Eubacterium rectale (ER), and their combined intervention (ER+FCP) on Type 2 diabetes (T2D)-related kidney injury in a rat model, using untargeted urinary...

2026-03-02 | MTBLS13958 | MetaboLights
ProteomicsQuantitative proteomic analysis reveals molecular adaptations in the hippocampal synaptic active zone of chronic mild stress-unsusceptible rats
Background: While stressful events are recognized as an important cause of major depressive disorder (MDD), some individuals exposed to life stressors maintain normal psychological functioning. Although the molecular mechanism(s) underlying this phenomenon remain unclear, abnormal transmission and p...
ORGANISM(S): Rattus norvegicus (Rat) 
2015-11-05 | PXD002540 | Pride
Rat hippocampus Triple tof 5600 Itraq Lc-ms/ms 
ProteomicsProteomics profiling of pediatric choroid plexus tumors
Aggresome is a para nuclear inclusion body that functions as a storage compartment for misfolded proteins. Our previous work revealed the presence of aggresomes in pediatric choroid plexus tumors (CPT). CPTs are rare neoplasms comprised of three pathological subgroups; choroid plexus carcinoma (CPC)...
ORGANISM(S): Homo sapiens (Human) 
2021-02-11 | PXD021076 | Pride
Human Carcinoma Cancer Choroid plexus Tissue Pappiloma Atypical Tumor Pediatric 
ProteomicsA Comprehensive map and functional annotation of human pituitary and thyroid proteome
A Comprehensive map and functional annotation of human pituitary and thyroid proteome
ORGANISM(S): Homo sapiens (Human) 
2017-07-07 | PXD006471 | Pride
Thyroid Pituitary Human 
ProteomicsElevated carbon dioxide levels lead to proteome-wide alterations for optimal growth of a fast-growing cyanobacterium, Synechococcus elongatus PCC 11801
Biological CO2 mitigation by photosynthetic microorganisms has emerged as a promising approach for generating biomass-based energy during the course of CO2 fixation. Additionally, cyanobacteria-based biofuels have also garnered immense attention lately because of the depleting fossil fuel reserves a...
ORGANISM(S): Synechococcus elongatus 
2019-04-23 | PXD011485 | Pride
Mrm. Proteomics Metabolic engineering Mass spectrometry Cyanobacteria Biofuels High co2 
ProteomicsLabel free SWATH proteomics reveals sex-biased proteins potentially associated with sex expression and modification in dioecious C. grandis
Dioecy is an important sexual system wherein, male and female flowers are borne on separate unisexual plants. Knowledge of sex-related differences can enhance our understanding in molecular and developmental processes leading to unisexual flower development. Coccinia grandis is a dioecious species b...
ORGANISM(S): Coccinia grandis 
2019-07-29 | PXD011064 | Pride
Sex expression Swath Stamen arrest Sex modification Label-free proteomics Pollen fertility 
ProteomicsIdentify Novel Iron–Transporting Proteins in Streptococcus pneumoniae
Streptococcus pneumoniae (S. pneumoniae) is a major human pathogen causing morbidity and mortality worldwide. Efficiently acquiring iron from the environment is critical for S. pneumoniae to sustain growth and cause infection. There are only three known iron-uptake systems in Streptococcal species r...
ORGANISM(S): Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) 
2018-10-26 | PXD003313 | Pride
Streptococcus pneumoniae Iron–transporting proteins Proteomics 
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