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ProteomicsRelating human gut metagenome and metaproteome
Gut microbiome research is rapidly moving towards the functional characterization of the microbiota by means of shotgun meta-omics. Here, we selected a cohort of healthy subjects from an indigenous and monitored Sardinian population to analyze their gut microbiota using both shotgun metagenomics and...
ORGANISM(S): human gut metagenome 
2017-07-19 | PXD005780 | Pride
Gut metagenome Gut metaproteome Metaproteomics 
ProteomicsImpact of Staphylococcus aureus infection on the late lactation goat milk proteome: new perspectives for monitoring and understanding mastitis in dairy goats
This investigation reports a differential proteomic analysis of the goat milk to evaluate and understand the protein changes induced by Staphylococcus spp. during a subclinical intramammary infection (IMI). A number of 9 milk samples from multiparous goats were selected for the study, 3 of which in ...
ORGANISM(S): Capra hircus (Goat) 
2020-04-09 | PXD017243 | Pride
Mastitis Label-free proteomics Milk Biological dataset Capra hircus Lc-ms/ms 
ProteomicsProteomic changes in the milk of water buffalo (Bubalus bubalis) with intramammary infection by Staphylococcus aureus and by non-aureus staphylococciProteomic changes in the milk of water buffalo (Bubalus bubalis) with intramammary infection by Staphylococcus aureus and by non-aureus staphylococci
The study reports a differential proteomic analysis of the Mediterranean buffalo milk to evaluate the changes induced by Staphylococcus spp. during a subclinical intramammary infection (IMI). A number of 12 quarter milk samples, 6 of which with somatic cell count (SCC) < 50,000 cells/mL and culture-...
ORGANISM(S): Bubalus bubalis 
2019-10-22 | PXD012355 | Pride
Mastitis Buffalo milk Label-free proteomics Lc-ms/ms 
ProteomicsBenchmarking low- and high-throughput protein cleanup and digestion methods for human fecal metaproteomics
Benchmarking low- and high-throughput protein cleanup and digestion methods for human fecal metaproteomics
ORGANISM(S): Homo sapiens (Human) human gut metagenome 
2024-05-31 | PXD049294 | Pride
Metaproteome Mass spectrometry Fasp Gut microbiota Sample preparation Multiwell plate 
ProteomicsMetaproteomic assessment of gut microbial and host functional perturbations in Helicobacter pylori-infected patients subjected to an antimicrobial protocol
The impact of therapeutic interventions on the human gut microbiota (GM) is a clinical issue of paramount interest given the strong interconnection between microbial dynamics and human health. Orally administered antibiotics are known to reduce GM biomass and modify GM taxonomic profile. However, th...
ORGANISM(S): Homo sapiens (Human) human gut metagenome 
2023-12-14 | PXD042946 | Pride
Antibiotics Metaproteomics Helicobacter Mass spectrometry Gut microbiota Human microbiome 
UnknownEpitope tagging of chromosomal genes in Salmonella.
Not available
S-EPMC65018 | biostudies-literature
ProteomicsMulti-omic biogeography of the gastrointestinal microbiota of a pre-weaned lamb
Here, we used reverse-phase liquid chromatography-coupled tandem mass spectrometry to study the pre-weaned lamb proteome and metaproteome in ten different gastrointestinal tracts: rumen, reticulum, omasum, abomasum, duodenum, jejunum, ileum, cecum, colon, and rectum.
ORGANISM(S): Microbiota Ovis aries 
2017-12-14 | PXD008192 | Pride
Ruminant Metaproteomics Mucosa Microbial community Sheep 
ProteomicsComparative secretome analysis of Staphylococcus aureus strains with different within-herd intramammary infection prevalence
This investigation reports a differential proteomic analysis of the secretome of six S. aureus strains belonging to two genotypes with opposite within-herd prevalence, GTB (high) and GTS (low), corresponding to sequence types (ST) 8 and 398, respectively. Total proteins released in the growth medium...
ORGANISM(S): Staphylococcus aureus 
2022-02-14 | PXD029571 | Pride
Mammary gland Mastitis Label-free proteomics Bacterial virulence Biological dataset Lc-ms/ms 
UnknownDraft Genome Sequence of Rhodotorula mucilaginosa, an Emergent Opportunistic Pathogen.
Not available
S-EPMC4392146 | biostudies-literature
UnknownClostridial Butyrate Biosynthesis Enzymes Are Significantly Depleted in the Gut Microbiota of Nonobese Diabetic Mice.
Not available
S-EPMC6200989 | biostudies-literature
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