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ProteomicsThe sulfur stress response and protein S-thioallylation caused by allicin and diallyl polysulfanes in Bacillus subtilis as revealed by transcriptomics and proteomics
In this study, we compared the transcriptome signatures under allicin and diallyl tetrasulfane (DAS4) exposure in the Gram-positive bacterium B. subtilis. We further used shotgun proteomics to unravel the overall S-thioallylomes provoked by allicin and DAS4. Allicin and DAS4 caused a similar thiol-s...
ORGANISM(S): Bacillus subtilis subsp. subtilis str. 168 
2019-12-09 | PXD013607 | Pride
Bacillus subtilis/ allicin/ diallyl polysulfane/ bacillithiol/ s-thioallylation 
ProteomicsThe human allicin-proteome: global protein S-thioallylation of by the garlic defence substance allicin and its biological effects
A single clove of edible garlic (Allium sativum L.) produces up to 5 mg of allicin (diallylthiosulfinate), a thiol-reactive sulfur-containing defence substance that gives injured garlic tissue its characteristic smell. Allicin induces apoptosis or necrosis in a dose-dependent manner but sublethal do...
ORGANISM(S): Homo sapiens (Human) 
2018-11-30 | PXD010201 | Pride
Interleukin il1 Il2 S-thioallylation Cytoskeleton Allicin Jurkat T-cells Protein modification Fibroblasts Cysteine Enolase Actin Zinc 
Transcriptomics5'-RNAseq of 5'-enriched primary coding RNA in Staphylococcus aureus wildtype under 30 min allicin stress to detect Transcription Start Sites
To detect Transcription Start sites (TSS) in Staphylococcus aureus a cDNA library enriched for primary 5′-transcripts according to Peifer-Sancar et al. (2013) was prepared and sequenced on Illumina MiSeq system to retrieve 5′-ends of primary transcripts. Cultivation was performed in Luria Bertani (L...
ORGANISM(S): Staphylococcus aureus 
2021-10-25 | E-MTAB-10889 | biostudies-arrayexpress
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