Vermis - OmicsDI

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Lab affiliation

Bernstein Professor Emeritus in Adult Psychiatry Department of Psychiatry and Behavioral Sciences University of Minnesota Medical School Minneapolis, Minnesota, USA (1)
Department of Chemistry, Imperial College London, Molecular Research Science Hub, 80 Wood Lane, London W12 0BZ, United Kingdom. The Francis Crick Institute, 1 Midland Road, London NW1 1AT, United Kingdom. (1)

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Impaired aggrephagy,abnormal vesicular trafficking and cellular stress, lead to protein aggregation,neurodegeneration and synaptic dysfunction in cerebellar vermis of children and adults with idiopathic autism

Autism spectrum disorder (ASD) is a debilitating neurodevelopmental disorder with genetic and environmental etiologies involving several brain areas exhibiting abnormalities of cognition and social behavior. Previous work showed involvement of synaptic abnormalities in dorsolateral prefrontal cortex...

ORGANISM(S): Homo sapiens (Human)

2025-08-25 | PXD061746 | Pride