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ProteomicsDeep proteomic and phosphoproteomic profiling of neuroblastoma treated with XPO1 inhibitor Selinexor
Neuroblastoma accounts for 15% of cancer-related deaths in children, highlighting an unmet need for novel therapies. Selinexor is a small molecule inhibitor of XPO1 that shuffles cargo proteins with a nuclear export sequence, many of which are essential for cancer growth and cell maintenance, from t...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD026454 | Pride
Tmtpro Phosphoproteome Selinexor Xpo1 Neuroblastoma Proteome 
ProteomicsDeep proteomic and phosphoproteomic profiling of DIPG responses to radiation therapy
Different DIPG tumor models have different responses to radiation therapy, which can be identified by quantitative proteomics/phospho-proteomics approach
ORGANISM(S): Homo sapiens (Human) 
2024-05-21 | PXD028285 | Pride
Cancer Radiation therapy Phosphoproteome Dipg Proteome 
ProteomicsDeep proteomic and phosphoproteomic profiling of Rhabdoid tumor response to IDA/SEL therapy
Different Rhabdoid tumors have different responses to idasanultin/selinexor therapy, which can be identified by quantitative proteomics/phospho-proteomics approach
ORGANISM(S): Homo sapiens (Human) 
2026-03-30 | PXD049344 | Pride
Human Pediatric Selinexor Idasanutlin Rhabdoid 
UnknownExploring CYP2D6 polymorphisms and angiotensin receptor blocker response in the Bai hypertensive population.
Not available
S-EPMC11221794 | biostudies-literature
UnknownA second new species of ice crawlers from China (Insecta: Grylloblattodea), with thorax evolution and the prediction of potential distribution.
Not available
S-EPMC2943926 | biostudies-literature
MetabolomicsPlasma metabolome alteration in dairy cows with left displaced abomasum before and after surgical correction
Left displaced abomasum (LDA) leads to substantial changes in the metabolism of dairy cows. Surgical correction of LDA can rapidly improve the health of cows; however, changes in metabolism following surgery are rarely described. To investigate the changes of plasma metabolome in cows with LDA befor...
2022-08-17 | MTBLS4126 | MetaboLights
MetabolomicsMetabolomic insights into the browning of the peel of bagging 'Rui Xue' apple fruit

BACKGROUND: Bagging is one of the most important techniques for the production of high-quality fruits. In the act of cultivation, we found a new kind of browning in peel of the apple fruit that occurs before harvest and worsens during the storage period. There are many studies on...

2021-04-09 | MTBLS2384 | MetaboLights
UnknownDrug or Toxic? A Brief Understanding of the Edible Corolla of Rhododendron decorum Franch. by Bai Nationality with Comparative Metabolomics Analysis.
Not available
S-EPMC11434486 | biostudies-literature
TranscriptomicsExpression data from MDA-MB-231 parental and xenograft tumor cells treated with Smac mimetic SM-164.
Small-molecule Smac mimetics target inhibitor of apoptosis (IAP) proteins to induce TNFα-dependent apoptosis in cancer cells and several Smac mimetics have been advanced into clinical development as a new class of anticancer drugs. However, preclinical studies have shown that only a small subset of...
ORGANISM(S): Homo sapiens 
2012-03-01 | E-GEOD-33827 | biostudies-arrayexpress
UnknownUpregulation of Yin-Yang-1 Associates with Proliferation and Glutamine Metabolism in Esophageal Carcinoma.
Not available
S-EPMC8961439 | biostudies-literature
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