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Drug addiction is a chronic relapsing brain disease. The alterations of glucose uptake and metabolism were found in the brain of drug addicts. Insulin mediates brain glucose metabolism and its abnormality could induce brain injury and cognitive impairment. Here, we established a rat model of phenoba...
ORGANISM(S): Rattus norvegicus (Rat) 
2020-10-29 | PXD021101 | Pride
Aroma is an important parameter for table grapes and wines; terpenes are typical compounds in Muscat-type grape cultivars and can be easily perceived by humans because of their low olfactory threshold. Volatile terpenes contribute directly to the aroma character, while glycoside-bound terpenes are p...
2019-11-15 | MTBLS968 | MetaboLights
Demyelinating disease is a disease of the nervous system in which the nerve demyelinating is the main or primary lesion, and the axon, cell body and glia are relatively lightly damaged. It can occur in the central nervous system or the peripheral nervous system. The demyelinating diseases of central...
ORGANISM(S): Homo Sapiens 
2020-12-09 | PXD023027 |
Metabolic reprogramming is a hallmark of cancer. Herein we discover that the key glycolytic enzyme pyruvate kinase M2 isoform (PKM2), but not the related isoform PKM1, is methylated by co-activator-associated arginine methyltransferase 1 (CARM1). PKM2 methylation reversibly shifts the balance of met...
2021-07-30 | MTBLS533 | MetaboLights
we performed DNA-affinity precipitation assay (DAPA) followed by mass spectrometry to identify the possible proteins that specifically bind to the 59-bp nucleotide sequence containing rs2280381 using U-937 cell nuclear extracts.
ORGANISM(S): Homo sapiens (Human) 
2022-02-26 | PXD029688 | Pride
iTRAQ-based quantitative proteomic technology was used to study the proteomic responses to food intake of C. nasus.
ORGANISM(S): Coilia Nasus 
2021-12-15 | PXD030433 |
Fe(II) can be oxidized by mixotrophic nitrate-reducing Fe(II)-oxidizing bacteria to Fe(III), leading to mineral precipitation. However, the effects of this process on the metabolism and reproduction ability of the Fe(II)-oxidizing bacterial cells have not yet been quantified. In this study, we inves...
ORGANISM(S): Acidovorax 
2026-01-01 | PXD072688 |
Global proteome data for 102 MTC samples, and phosphoproteome data for 74 MTC samples
ORGANISM(S): Homo Sapiens 
2022-04-01 | PXD032887 |
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