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ProteomicsQuantitative phosphoproteomic and physiological analyses provide insights into the formation of the variegated leaf in Catalpa fargesii
To unveil the role of posttranslational modification in the variegated phenotype, we conducted global quantitative phosphoproteomic analysis on different leaf color sectors of Maiyuanjinqiu and the corresponding of Catalpa fargesii using Ti4+-IMAC phosphopeptide enrichment. 3778 phosphorylated sites...
ORGANISM(S): Catalpa fargesii 
2019-11-12 | PXD013065 | Pride
Catalpa fargesii  phosphoproteomics  variegated leaf  regulated mechanism 
MetabolomicsComparison analysis of metabolite profiling in seeds and bark of Ulmus parvifolia, a Chinese medicine species

Ulmus parvifolia (U. parvifolia) was traditionally used in the treatment of some diseases such as inflammation, diarrhea and fevers. With the wide application of molecular biotechnology in plant development and utilization, the pharmaceutical value and chemical composition of th...

2024-01-09 | MTBLS4572 | MetaboLights
ProteomicsGlobal lysine acetylome analysis of Picea asperata somatic 1 embryos during partial desiccation
By the combination of affinity enrichment and high-resolution LC-MS/MS analysis, large-scale lysine acetylome analysis was performed in picea asperata. Altogether, 1,360 lysine acetylation sites in 717 protein groups were identified. Intensive bioinformatic analysis was then carried out to annotate ...
ORGANISM(S): Picea asperata 
2018-10-26 | PXD005042 | Pride
Picea asperata Acetylome Lc-msms 
ProteomicsProteomic analyses of embryogenic tissues in Picea balfouriana treated by 6-BAP
In this study, iTRAQ technology was applied to characterize the genes and proteins that are differentially expressed among tissues under the influence of different levels of 6-BAP(2.5 μM, 3.6 μM and 5 μM). There were two biological and three technological replicates for each treatment. Two biologica...
ORGANISM(S): Picea likiangensis var. rubescens 
2014-09-23 | PXD001022 | Pride
Picea balfouriana 6-bap Embryogenic tissues Lc-ms/ms 
TranscriptomicsTranscriptomic analysis reveals the involvement of canonical Wnt signaling in zebrafish gonad differentiation
Zebrafish males undergo a juvenile ovary to testis type gonadal transformation process. To understand how juvenile ovary-to-testis transformation in zebrafish is genetically regulated, we compared the transcriptomes of juvenile ovary (JO) and juvenile ovotestis (JOT) samples at 35 dpf using the Gona...
ORGANISM(S): Danio rerio 
2013-12-27 | E-MEXP-3879 | biostudies-arrayexpress
ProteomicsImmunoprecipitation and mass spectrometry (IP-MS) on KAT6A chimeras
Despite KAT6A chimeras potent oncogenic activity, the mechanisms by which KAT6A fusion proteins achieve genomic specificity and drive leukemogenesis remain poorly understood. Previous studies suggest that the leukemogenic potential of KAT6A-TIF2 depends on its chromatin-binding ability rather than i...
ORGANISM(S): Homo sapiens (Human) 
2025-08-08 | PXD061491 | Pride
Human Ip-ms. Kat6a fusion Immunoprecipitation Kat6a n-terminus 
ProteomicsMass spectrometry analysis of post-translational modifications of K/C-III-expressing HEK293T cells treated by A485 for 6 and 12 hours
To determine whether CBP/P300 HAT activity is essential for leukemia cell maintenance, we utilized the selective acetyltransferase inhibitor A485. Mass spectrometry analysis of post-translational modifications showed that A485 treatment of K/C-III-expressing HEK293T cells for 6 and 12 hours signific...
ORGANISM(S): Homo sapiens (Human) 
2025-08-08 | PXD061565 | Pride
Human A485 Post-translational modification K/c-iii Lc-faims-ms/ms 
Proteomicscapsaicin ameliorates rheumatoid arthritis via ROS-mediated apoptosis in fibroblast-like synoviocytes
In this project we discovered that CAP not only reduces joint swelling in arthritic model mice but also exhibits anti-inflammatory and antiproliferative effects on fibroblast-like synoviocytes (FLS). By synthesizing alkyne-tagged CAP probes and employing activity-based protein profiling (ABPP), we i...
ORGANISM(S): Homo Sapiens 
2024-11-07 | PXD057639 |
ProteomicsInhibition Peroxiredoxin-2 by capsaicin ameliorates rheumatoid arthritis via ROS-mediated apoptosis in fibroblast-like synoviocytes
In this project we discovered that CAP not only reduces joint swelling in arthritic model mice but also exhibits anti-inflammatory and antiproliferative effects on fibroblast-like synoviocytes (FLS). By synthesizing alkyne-tagged CAP probes and employing activity-based protein profiling (ABPP), we i...
ORGANISM(S): Homo Sapiens 
2024-11-12 | PXD057819 |
ProteomicsIdentification and analysis of small proteins and short open reading frame encoded peptides in Hep3B cell
The small proteins and short open reading frames encoded peptides (SEPs) are of fundamental importance because of their essential roles in biological processes. However, the annotation or identification of them is challenging, in part owing to the limitation of the traditional genome annotation pipe...
ORGANISM(S): Homo Sapiens 
2021-05-05 | PXD025813 |
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