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Protein L-isoaspartyl/D-aspartyl Methyltransferase (PCMT1) plays a pivotal role in repairing a spontaneous post-translational modification (PTM) of L-isoaspartyl residues resulted from asparagine deamidation or aspartate isomerization. This PTM is particularly important for extracellular matrix (ECM...
ORGANISM(S): Mus musculus (Mouse) 
2025-03-18 | PXD047057 | Pride
The SARS-CoV-2 Delta variant is more contagious than WT and causes severe symptoms.To understand the elevated fusogenicity of Delta, we used LC-MS/MS to characterize the site specific N-linked glycan of spike protein in SARS-CoV-2 Delta variant virions.The glycan analysis revealed increased oligoman...
ORGANISM(S): Severe acute respiratory syndrome coronavirus 2 
2023-05-10 | PXD033342 | Pride
This project aims to elucidate the molecular mechanisms by which the gut microbial metabolite β-guanidinopropionic acid (β-GPA) alleviates hyperlipidemic periodontitis (HPD). We performed Tandem Mass Tag (TMT) based quantitative proteomic analysis on periodontal tissues from HPD model mice versus th...
ORGANISM(S): Mus Musculus 
This study demonstrated that circadian gene clock plays an important role in the regulation of mitochondrial homeostasis. In this process, CLOCK interacts with PUF60 and affects the mRNA stability of Drp1.
ORGANISM(S): Mus Musculus 
In this study, using proteomics study of urine samples from patients with primary APS (PAPS) and healthy controls (HC), we identified several proteins that discriminated Obstetric APS (OAPS) and Thrombotic APS (TAPS) from each other, as well as from HC.
ORGANISM(S): Homo Sapiens 
Analysis of protein interaction between platelets and SARS-CoV-2 envelope protein
ORGANISM(S): Homo Sapiens Severe Acute Respiratory Syndrome Coronavirus 2 
2023-08-08 | PXD037073 |
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