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ProteomicsLyso-IP from Wdr7 iKO MEFs
Lysosomes were enriched from Wdr7 iKO MEFs stably expressing TMEM192-3xHA (Bait) or TMEM192-2xFlag (Ctrl) via lysosomal immunoprecipitation (Lyso-IP) using PierceTM anti-HA magnetic beads to analyze changes in the lysosomal protein content upon induced depletion of Wdr7.
ORGANISM(S): Mus musculus (Mouse) 
2026-06-25 | PXD070950 | Pride
Lyso-ip Mefs V-atpase Tmem192 Lysosomes Iko Wdr7 
ProteomicsProteome from Wdr7 iKO MEFs
Post-nuclear supernatants from Wdr7 iKO MEFs were analyzed.
ORGANISM(S): Mus musculus (Mouse) 
2026-06-25 | PXD070900 | Pride
Mefs V-atpases Lysosomes Iko Lysosomal enzymes Wdr7 
ProteomicsSecretome from Wdr7 iKO MEFs
Extracellular medium was collected from Wdr7 iKO MEFs after 24h in OptiMEM, and secreted proteins were analyzed.
ORGANISM(S): Mus musculus (Mouse) 
2026-06-25 | PXD070740 | Pride
Mefs Secreted proteins Secretome Lysosomes Iko Wdr7 Lysosomal enzymes 
UnknownThe priming factor CAPS1 regulates dense-core vesicle acidification by interacting with rabconnectin3β/WDR7 in neuroendocrine cells.
Not available
S-EPMC6579465 | biostudies-literature
UnknownCalycosin inhibits the in vitro and in vivo growth of breast cancer cells through WDR7-7-GPR30 Signaling.
Not available
S-EPMC5667511 | biostudies-literature
TranscriptomicsGenome-wide CRISPR screen Identifies Host Dependency Factors for Influenza A Virus Infection
In this study, we performed a genome-wide CRISPR screen in A549 cells to identify host genes that are required forInfluenza A virus (IAV) infection.Amongst the identified genes, WDR7, CCDC115, TMEM199 and CMTR1 conferred strong protection against IAV infection when they were CRISPR-deleted without i...
ORGANISM(S): Homo sapiens 
2019-11-30 | GSE141171 | GEO
UnknownIdentification of Host Factors for Rift Valley Fever Phlebovirus.
Not available
S-EPMC10675714 | biostudies-literature
UnknownIdentification of host factors for Rift Valley Fever Phlebovirus.
Not available
S-EPMC10557628 | biostudies-literature
GenomicsGenome-wide CRISPR screen Identifies Host Dependency Factors for Influenza A Virus Infection
Genome-wide CRISPR screen Identifies Host Dependency Factors for Influenza A Virus Infection
PRJNA592532 | ENA
Genomics
BRCA1, BRCA2, RAD51, and other DSB repair factors are regulated by CRL4/DDB1/WDR7
PRJNA784996 | ENA
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