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ProteomicsAPEX2 mediated proximity labeling to investigate the proximal proteome of mitochondria tethered ULK1 in wild type and fip200 knock down cells
The object of this project is to investigate the proximal proteome of ULK1 during mitophagy and the effects of a FIP200 knock down using the APEX2-mediated proximity labeling system. APEX2-ULK1 or APEX2 was fused to 2xFKBP-myc and stably expressed in a cell line stably expressing a truncated FIS1-FR...
ORGANISM(S): Homo sapiens (Human) 
2024-10-12 | PXD047277 | Pride
Fip200 Mitophagy Autophagy Frb-rapalog-fkbp interaction Ulk1 Apex2 Er 
ProteomicsEndosulfines Igo1 and Igo2 promote hyperosmotic stress signaling via inhibition of protein phosphatase 2A
The hyperosmotic stress response in budding yeast is a paradigm for cellular responses to physicochemical stimuli that is often used for modeling signal transduction pathways. Here, we describe the phosphatase PP2A-Cdc55 as a novel master regulator of hyperosmotic stress signaling. We show that its ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2021-11-02 | PXD019646 | Pride
Stress response Phosphorylation Igo2 Gis1 Igo1 Phosphatase Pp2a Saccharomyces cerevisiae Quantitative proteomics Rph1 Hyperosmotic stress Stress signaling Cdc55 Endosulfines 
TranscriptomicsEpstein-Barr virus maintains lymphomas via its miRNAs
EpsteinM-bM-^@M-^PBarr virus (EBV) has evolved exquisite controls over its host cells, human B lymphocytes, not only directing these cells during latency to proliferate and thereby expand the pool of infected cells, but also to survive and thereby persist for the lifetime of the infected individual....
ORGANISM(S): Homo sapiens 
2013-04-30 | E-GEOD-44769 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of different strains of yeast exposed to arsenic stress
Effect of arsenic stress on cellular metabolism, respectively on transcription factors in the yeast Saccharomyces cerevisiae
ORGANISM(S): Saccharomyces cerevisiae 
2008-09-02 | E-MEXP-1075 | biostudies-arrayexpress
Transcriptomicsc-Myc is a universal amplifier of gene expression [Microarray]
The c-Myc HLH-bZIP protein has been implicated in physiological or pathological growth, proliferation, apoptosis, metabolism and differentiation at the cellular, tissue or organismal levels via regulation of numerous target genes. In part due to the incomplete inventory and functional accounting of ...
ORGANISM(S): Mus musculus 
2012-09-27 | E-GEOD-37222 | biostudies-arrayexpress
Genomicsc-Myc is a universal amplifier of gene expression
This SuperSeries is composed of the following subset Series: GSE37222: c-Myc is a universal amplifier of gene expression [Microarray] GSE37229: c-Myc is a universal amplifier of gene expression [ChIP-Seq] Refer to individual Series
ORGANISM(S): Mus musculus 
2012-09-27 | E-GEOD-37230 | biostudies-arrayexpress
Genomicsc-Myc is a universal amplifier of gene expression [ChIP-Seq]
The c-Myc HLH-bZIP protein has been implicated in physiological or pathological growth, proliferation, apoptosis, metabolism and differentiation at the cellular, tissue or organismal levels via regulation of numerous target genes. In part due to the incomplete inventory and functional accounting of ...
ORGANISM(S): Mus musculus 
2012-09-27 | E-GEOD-37229 | biostudies-arrayexpress
UnknownRNA editing of filamin A pre-mRNA regulates vascular contraction and diastolic blood pressure
Not available
S-SCDT-EMBOJ-2016-94813 | biostudies-other
UnknownViral resuppression and detection of drug resistance following interruption of a suppressive non-nucleoside reverse transcriptase inhibitor-based regimen.
Not available
S-EPMC2745911 | biostudies-literature
GenomicsDATA_SET_ICGC_PedBrainTumor_Medulloblastoma_Discovery_Cohort - samples
DATA_SET_ICGC_PedBrainTumor_Medulloblastoma
EGAD00001000122 | EGA
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