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ProteomicsLC-MS/MS for harmaline-treated mice cerebellar cortex
Harmaline-induced tremor mice model has been well-recognized as a mature pharmacological model for ET, but his model has always been used to test drugs, the exact underlying mechanism of this mouse model has never been fully understood. This project is to provide a novel inspection for ET targeted t...
ORGANISM(S): Mus musculus (Mouse) 
2026-01-05 | PXD055985 | Pride
Cerebellar cortex Harmaline Mice Lc-ms/ms 
ProteomicsIdentification of the expression of a novel protein in MCF7 cells
The novel protein GT3-INCP (GATA3-interacting cryptic protein) that were identified by mass spectrometry in the MCF7 cells stably expressing FLAG-tagged CDS, in the presence of the native 5’UTR.
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037137 | Pride
Human Orfs Gt3-incp Brca Er Gata3 
ProteomicsIdentification of the expression of a novel protein in MCF7 cells
The novel protein GT3-INCP (GATA3-interacting cryptic protein) that were identified by mass spectrometry in the MCF7 cells stably expressing FLAG-tagged CDS, in the presence of the native 5’UTR.
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD031778 | Pride
Human Orfs Gt3-incp Brca Er Gata3 
ProteomicsImmunoprecipitates of KDM1A in HepG2 cells with stably overexpressed KDM1A
KDM1A requires an adaptor protein with specific DNA-binding activity to recognize chromatin sequence. We constructed HepG2 cells stably overexpressing KDM1A-Flag tag using lentivirus. We performed Co-IP with Flag-gel and we used LC-MS to determine the immunoprecipitates of KDM1A.
ORGANISM(S): Homo Sapiens 
2023-05-19 | PXD043284 |
ProteomicsA Tissue-Specific Atlas of Mouse N-Glycoproteome
In this study, we employed StrucGP to generate the first high-resolution and site-specific N- glycoproteomic atlas across 24 diverse mouse tissues. This comprehensive dataset provides an unprecedented insight into the tissue-specific landscape of N-glycosylation, revealing how distinct glycan struct...
ORGANISM(S): Mus Musculus 
2025-05-07 | PXD063701 |
ProteomicsQuantitative glycoproteomic, proteomic, and phosphoproteomic analysis of aged mouse ovary
In this work, we investigate the differences of site-specific N-glycosylation between young (2-month-old) and middle-aged (12-month-old) mouse ovarian tissues by integrating N-glycoproteomics and proteomic approaches with tandem mass tag (TMT) labeling.To identify signalling pathways associated with...
ORGANISM(S): Mus Musculus 
2024-09-14 | PXD056126 |
ProteomicsFunctional Optic Tract Rewiring via Subtype- and Target-specific Axonal Regeneration and Presynaptic Activity Enhancement
We showed that with genetic manipulation as Pten/Socs3 knockout (KO), CNTF overexpression and Lipin1 knockdown (PSCL), RGCs could regenerate and reinnervate into OPN nuclei after pre-OPN optic tract injury. We then performed single-cell RNA sequencing on OPN-projecting retinal ganglion cells and pro...
ORGANISM(S): Mus Musculus 
2024-05-25 | PXD052573 |
ProteomicsIdentifying glycolysis in mitochondria as a new perspective on the pathogenesis of retinitis pigmentosa
The interaction proteins were obtained by immunoprecipitation (IP) of VWA8 using retinal pigment epithelium cell lysate.
ORGANISM(S): Homo Sapiens 
2026-03-29 | PXD076332 |
Proteomicscomparative proteomics studies of the wild strain SC1401 and the tfoX deficient strain
Natural transformation, as one of the horizontal gene transfer (HGT) modes of bacteria, allows bacteria to actively uptake foreign DNA under natural conditions and integrate it into their genome through homologous recombination. Natural transformation plays an vital role in the rapid spread of patho...
ORGANISM(S): Glaesserella Parasuis 
2022-03-17 | PXD032382 |
ProteomicsBCAA insufficiencies lead to premature ovarian insufficiency via ceramide induced elevation of ROS
Premature ovarian insufficiency (POI) is a disease featured by early menopause before 40 years of age, accompanied by an elevation of follicle-stimulating hormone (FSH). Though POI affects many aspects of women’s health, its major causes remain unknown. Many clinical studies have shown that POI pati...
ORGANISM(S): Homo Sapiens 
2022-10-13 | PXD037353 |
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