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ProteomicsAcetylome analysis of HepG2 cells after treatment with PBS or LukS-PV
We previously reported that LukS-PV, a component of Panton-Valentine interleukin (PVL), has anti-leukaemic activity, inducing differentiation, increasing apoptosis and inhibiting proliferation of acute myeloid leukaemia (AML) cells. In addition, our study showed that LukS-PV could inhibit the progre...
ORGANISM(S): Homo sapiens (Human) 
2026-01-02 | PXD057287 | Pride
Luks-pv  hepg2  acetylome analysis  lc-ms/ms 
ProteomicsHypothalamic Proteomics analysis of lipopolysaccharide (LPS)-induced depressed mice
Hypothalamic dysfunction is a key pathological factor in inflammation-associated depression. In the present study, isobaric tags for relative-absolute quantitation (iTRAQ) combined with mass spectrometry were employed to detect the proteomes in the hypothalamus of the lipopolysaccharide (LPS)-induce...
ORGANISM(S): Mus musculus (Mouse) 
2020-01-09 | PXD016040 | Pride
Depression Hypothalamus Lipopolysaccharide Itraq lc-ms/ms Brain tissue 
TranscriptomicsRole of SIRT1 in diet-induced metabolic diseases
The purpose of this study is to investigate the role of SIRT1 in high-fat diet-induced liver steatosis and insulin resistance. SIRT1 is a nuclear enzyme that could remove an acetyl-group from target proteins by using NAD as co-substrate. Homologs of this protein in yeast and the roundworm C. elegans...
ORGANISM(S): Mus musculus 
2012-07-31 | E-GEOD-39778 | biostudies-arrayexpress
MetabolomicsThe trans-omics landscape of COVID-19
The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
ProteomicsThe protein profile of mammary gland and tumors between Brca1-WT and MT miece by DIA-MS(DIA-data)
WT mammary gland(WTMG),mutant-MG(MTMG),WT breast tumors(WTBT),MTBT and MTBT-adjacent MG were collected to do data-independent acquisiton(DIA)mass to find the intrinsic factors that is associated with Brca1-deficiency induced breast cancer.
ORGANISM(S): Mus musculus (Mouse) 
2022-02-20 | PXD030328 | Pride
Breast cancer Mammary gland Mouse Brca1-deficiency Dia-ms 
ProteomicsThe protein profile of mammary gland and tumors between Brca1-WT and MT miece by DIA-MS(DDA data)
WT mammary gland(WTMG),mutant-MG(MTMG),WT breast tumors(WTBT),MTBT and MTBT-adjacent MG were collected to do data-independent acquisiton(DIA)mass to find the intrinsic factors that is associated with Brca1-deficiency induced breast cancer.
ORGANISM(S): Mus musculus (Mouse) 
2022-02-20 | PXD030355 | Pride
Breast cancer Mammary gland Mouse Brca1-deficiency Dia-ms 
TranscriptomicsTranscriptional analyses of mandarins seriously infected by “Candidatus Liberibacter asiaticus”
HLB is suggested to be caused by the phloem-limited fastidious prokaryotic α-proteobacterium “Candidatus Liberibacter spp.” Previous studies focused on the proteome and transcriptome analyses of citrus 5 to 35-week-after “Ca. L. spp.” inoculation. In this study, gene expression profiles was analyzed...
ORGANISM(S): Citrus reticulata 
2015-04-10 | E-GEOD-67376 | biostudies-arrayexpress
ProteomicsExploring the mechanism of action of Canmei formula against colorectal adenoma through multi-omics technique
Background: Canmei formula (CMF) is a traditional Chinese medicine compound with definite effect on the prevention and treatment of colorectal adenoma (CRA). It can prevent the transformation of intestinal inflammation to cancer. This study explored the mechanism of action of CMF in anti-CRA using ...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-16 | PXD029296 | Pride
Human Colorectal adenoma Lc-ms 
Genomicsena-DATASET-BGI-26-11-2015-07:58:13:440-13 - samples
Esophageal cancer is one of the most aggressive cancers and the sixth leading cause of cancer death worldwide1. Approximately 70% of the global esophageal cancers occur in China and over 90% histopathological forms of this disease are esophageal squamous cell carcinoma (ESCC)2-3. Currently, there ar...
EGAD00001001691 | EGA
GenomicsWhole-genome sequencing in 14 cases and whole-exome sequencing in 90 cases of Chinese ESCC
Esophageal cancer is one of the most aggressive cancers and the sixth leading cause of cancer death worldwide1. Approximately 70% of the global esophageal cancers occur in China and over 90% histopathological forms of this disease are esophageal squamous cell carcinoma (ESCC)2-3. Currently, there ar...
EGAS00001001487 | EGA
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