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UnknownMogroside V Ameliorates Spinal Cord Injury by Inhibiting M1 Microglia Polarization.
Not available
S-EPMC12657585 | biostudies-literature
ProteomicsActivation of Akt, Nrf2, and NF-κB signal transduction pathways in the liver as a mechanism of survival for torpid Myotis ricketti Bats
Unfolded protein accumulation in the lumen of endoplasmic reticulum (ER) induced by cold exposure is termed UPRER. Some mammals hibernate to overcome cold winter. We investigated whether hibernating bats are under UPRER and activate Akt, Nrf2, and NF-κB signaling pathways that are critical for cell ...
ORGANISM(S): Myotis ricketti 
2020-11-17 | PXD016109 | Pride
Mitochondria Eif2 Akt Hibernation Upr And lc-ms/ms Nf-κb Bats Proteomics Liver 
UnknownIn Situ Polymerized Polyfluorinated Crosslinked Polyether Electrolytes for High-Voltage Lithium Metal Batteries.
Not available
S-EPMC12288804 | biostudies-literature
TranscriptomicsHUVECs with endogenous or overexpressed GPR4 treated with pH 8.4 (control) or pH 6.4 for 5 h
Acidic tissue microenvironment is commonly found in a variety of pathophysiological conditions. GPR4 is a proton-sensing G protein-coupled receptor that is fully activated by acidic extracellular pH but has lesser activity at the physiological pH 7.4 and minimal activity at more alkaline pH. To dete...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-40060 | biostudies-arrayexpress
MetabolomicsThe Inhibition of B7H3 by 2-HG Accumulation Is Associated With Downregulation of VEGFA in IDH Mutated Gliomas
B7H3 (also known as CD276) is a co-stimulator checkpoint protein of the cell surface B7 superfamily. Recently, the function beyond immune regulation of B7H3 has been widely studied. However, the expression preference and the regulation mechanism underlying B7H3 in different subtypes of gliomas is ra...
2021-05-26 | MTBLS2692 | MetaboLights
UnknownA novel cathode interphase formation methodology by preferential adsorption of a borate-based electrolyte additive.
Not available
S-EPMC11312368 | biostudies-literature
MetabolomicsSalmonella Typhimurium reprograms macrophage metabolism via T3SS effector SopE2 to promote intracellular replication and virulence

Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infected with S. Typhimurium exhibit upregulated glycolysis and decreased serine synthesis, leading to accumulation of glycolytic intermediates. The effects on...

2024-05-22 | MTBLS2347 | MetaboLights
ProteomicsHuman serum N-linked intact glycopeptides LC-MS/MS
Large-scale identification of N-linked intact glycopeptides by liquid chromatography coupled tandem mass spectrometry (LC-MS/MS) in human serum is challenging due to the wide dynamic range of serum protein abundances, the lack of a complete serum N-Glycan database and the existence of non-specifical...
ORGANISM(S): Armoracia rusticana Homo sapiens (Human) Gallus gallus (Chicken) 
2020-04-21 | PXD015622 | Pride
N-linked intact glycopeptide Co-elution Spectral library search Human serum Isotopic distribution 
Proteomicsproteomics conducted in control and KIF11-depleted HRECs
This dataset includes raw data from proteomics conducted in control and KIF11-depleted HRECs.
ORGANISM(S): Homo sapiens (Human) 
2026-02-13 | PXD074452 | Pride
Endothelial cells Kif11 Human Retina 
ProteomicsLysine acetylation contributes to artificial ageing in wheat (Triticum aestivum L.) seeds.
In this work, the role of protein acetylation modification in wheat aging was studied using TMT labelling, enrichment of acetylation peptides and quantitative proteomics strategy of high-resolution liquid chromatography-mass spectrometry. A total of 1663 acetylation sites were identified on 892 prot...
ORGANISM(S): Triticum aestivum (Wheat) 
2023-03-10 | PXD034134 | Pride
Lysine acetylation  artificial ageing  wheat 
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