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ProteomicsS.pombe mitochondrial proteome regulation under heat stress
To explore the molecular regulatory mechanisms of the mitochondrial proteome of S. pombe under temperature-stress stress, the heat shocked-treated and -untreated S. pombe strain for culturing 12 h were obtained by the Parallel accumulation-serial fragmentation combined with data independent acquisit...
ORGANISM(S): Schizosaccharomyces pombe 972h- 
2026-08-24 | PXD060104 | Pride
Mitochondria Schizosaccharomyces pombe Heat stress 
ProteomicsFMNL2/SRC-mediated androgen receptor translocation into the nucleus promotes enzalutamide resistance of prostate cancer
Enzalutamide, a second-generation androgen receptor (AR) antagonist, has represented the association with improved overall survival in men with prostate cancer (PCa). However, PCa patients receiving enzalutamide will eventually develop resistance through various mechanisms without effective regimens...
ORGANISM(S): Homo sapiens (Human) 
2025-01-13 | PXD059539 | Pride
Ar Fmnl2 Prostate cancer，enzalutamide resistance 
ProteomicsProteome Profiling of Endogenous and Potential S-nitrolysation in Colorectal Cancer
Background. As a common cancer with high incidence rate and mortality, colorectal cancer (CRC) is seriously threatening human health. Nitric oxide (NO) mediated protein S-nitrosylation (SNO) is of great significance in the occurrence and development of CRC, melanoma, breast cancer and other cancers....
ORGANISM(S): Homo Sapiens 
2023-01-13 | PXD039376 |
ProteomicsEP3 deletion in macrophages aggravates diet-induced obesity in mice by suppressing SPARC
Macrophages are primary immune cells involved in obesity-triggered chronic low-grade inflammation in adipose tissues. Prostaglandin (PG) E2, mainly generated from macrophages, can regulate adipose tissue remodeling. Here, we observed that PGE2 receptor subtype 3 (EP3) was remarkably downregulated in...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-25 | PXD063443 | Pride
Macrophage Obesity Sparc E-prostanoid 3 receptor 
UnknownFusarium and allied fusarioid taxa (FUSA). 1.
Not available
S-EPMC9355104 | biostudies-literature
UnknownEstablishment and verification of a TME prognosis scoring model based on the acute myeloid leukemia single-cell transcriptome.
Not available
S-EPMC11349878 | biostudies-literature
ProteomicsNucleation of DNA Repair Factors by FOXA1 Links DNA Demethylation and Transcriptional Pioneering
We report that the winged helix transcription factor FOXA1 is unexpectedly associated with components of single and double stranded-DNA repair complexes. Biochemical studies and high-throughput approaches validated the hierarchical composition of this FOXA1-nucleated machinery and revealed the depen...
ORGANISM(S): Homo sapiens (Human) 
2016-06-08 | PXD004271 | Pride
Human Lc-msms 
UnknownBacteriocin Microcin J25's antibacterial infection effects and novel non-microbial regulatory mechanisms: differential regulation of dopaminergic receptors.
Not available
S-EPMC11559059 | biostudies-literature
UnknownFingolimod as a potent anti-Staphylococcus aureus: pH-dependent cell envelope damage and eradication of biofilms/persisters.
Not available
S-EPMC12083125 | biostudies-literature
UnknownEmergence of a tet(M) Variant Conferring Resistance to Tigecycline in Streptococcus suis.
Not available
S-EPMC8417041 | biostudies-literature
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