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ProteomicsDifferential Lysis Approach Enables Selective Extraction of Taxon-Specific Proteins for Gut Metaproteomics
A differential lysis approach was developed with different strength of lysis buffers (urea and/or sodium dodecyl sulfate) and applied on human stool samples to separate different microbial species to increase the depth of metaproteomic measurements. We showed that the lysates dominating by proteins ...
ORGANISM(S): Escherichia coli 
2023-03-27 | PXD016787 | Pride
Human Lc-msms Gut microbiome 
ProteomicsSP3-PELSA: A Rapid and Sensitive Approach for Studying Protein-Ligand Interaction with Limited Samples
SP3-PELSA, a modified peptide-centric local stability assay integrated with SP3 sample preparation, enables fivefold faster processing, enhanced peptide recovery (especially for hydrophobic peptides and low-amount samples), and superior performance in drug target discovery, holding great potential f...
ORGANISM(S): Homo Sapiens 
2025-12-10 | PXD071732 |
ProteomicsA C-terminal tail deletion of histidine kinase WalK/VicK disrupted transcriptional regulation in Streptococcus mutans
An essential two-component system WalRK is required for biofilm formation of streptococcus mutans mainly through transcriptional regulations.
ORGANISM(S): Streptococcus Mutans Ua159 
PXD028893 |
MetabolomicsGNPS - Proteomic and Metabolomic Characterization of COVID-19 Patient Sera MRMHR
Targeted mass spectrometric assays for the 22 proteins in a second test cohort containing 19 COVID-19 patients
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-30 | MSV000085515 | GNPS
MetabolomicsGNPS - Proteomic and Metabolomic Characterization of COVID-19 Patient Sera
Early detection and effective treatment of severe COVID-19 patients remain major challenges. Here, we performed proteomic and metabolomic profiling of sera from 46 COVID-19 and 53 control individuals. We then trained a machine learning model using proteomic and metabolomic measurements from a traini...
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 (ncbitaxon:2697049) Homo Sapiens (ncbitaxon:9606) 
2020-05-29 | MSV000085507 | GNPS
ProteomicsProteomic and Metabolomic Characterization of COVID-19 Patient Sera
Early detection and effective treatment of severe COVID-19 patients remain major challenges. Here, we performed proteomic and metabolomic profiling of sera from 46 COVID-19 and 53 control individuals. We then trained a machine learning model using proteomic and metabolomic measurements from a traini...
ORGANISM(S): Severe Acute Respiratory Syndrome Coronavirus 2 (ncbitaxon:2697049) Homo Sapiens (ncbitaxon:9606) 
2020-05-29 | MSV000085507 | MassIVE
ProteomicsProteomic and Metabolomic Characterization of COVID-19 Patient Sera MRMHR
Targeted mass spectrometric assays for the 22 proteins in a second test cohort containing 19 COVID-19 patients
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-05-30 | MSV000085515 | MassIVE
ProteomicsProteomics Landscape of Diverse Serological Patterns in COVID-19
Serological test is a powerful tool to help clinicians assess the patients’ status during COVID-19 treatment. Highly diverse serological outcomes as exemplified by the negative or overly high IgG and IgM expressions are frequently reported but never elucidated interpreted with molecular insights. We...
ORGANISM(S): Homo Sapiens 
2023-01-27 | PXD039722 |
ProteomicsProteomic Analysis of Inactivated and Sterilized Sera might be Applied to Monitoring the Disease Course of COVID-19
We analyzed the proteome of 320 inactivated and sterilized sera from COVID-19 patients and controls.
ORGANISM(S): Homo Sapiens 
2020-11-19 | PXD022751 |
ProteomicsExplore the proteomics characteristics of urine and serum from COVID-19 patients
we obtained the proteome profiling of serum and urine specimen collected from 50 COVID-19 patients and 40 healthy subjects. We then used TMT-labeled proteomics and quantified 1,494 and 3,854 proteins in serum and urine, respectively. We then explored the pathogenic characteristics in body fluids aft...
ORGANISM(S): Homo Sapiens 
2021-12-30 | PXD030662 |
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