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ProteomicsProfiling of human lung tissues on 11 normal control, 11 patient and 11 corresponding mouse xenograft tumours
The total protein expression level of 11 paired human normal, human lung cancer samples and correspoding mouse xenograft samples were analyzed by LC-MS/MS. These protein expression data were than compared with corresponding DNA copy number changes and mRNA expression level changes among these sampl...
ORGANISM(S): Homo sapiens (Human) 
2014-12-04 | PXD000853 | Pride
Proteomics Mouse xenograft Human lung tumor 
ProteomicsThe deubiquitinase USP7 stabilizes Maf proteins to promote myeloma cell survival
USP7, as a deubiquitination enzyme, controls ubiquitination and stability of Maf family proteins. USP7 promotes Maf transcriptional activity. Moreover, USP7 is overexpressed in multiple myeloma cells and its expression level is negatively correlated to the survival of myeloma patients.
ORGANISM(S): Homo sapiens (Human) 
2019-12-16 | PXD016020 | Pride
Usp7 Myeloma Deubiquitinase Maf 
ProteomicsCancer proteome and metabolite changes linked to SHMT2
To screen for proximate and interacting proteins of SHMT2 in HeLa cells, the BioID method was employed, which consists of biotinylation of proteins in the vicinity of FlagBirAR118G –SHMT2 followed by streptavidin-based affinity capture and mass spectrometry identification. Experimental procedures we...
ORGANISM(S): Homo sapiens (Human) 
2020-08-12 | PXD004629 | Pride
Streptavidin Shmt2 Ms Bioid 
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