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Numerous studies found intestinal microbiota alterations which are thought to affect the development of various diseases through the production of gut-derived metabolites. However, the specific metabolites and their pathophysiological contribution to cardiac hypertrophy or heart failure progression ...
2021-12-08 | MTBLS3174 | MetaboLights
We present a comprehensive proteomic dataset of binding proteins for all 17 members of the poly(ADP-ribose) polymerase (PARP) family, generated using the TurboID proximity labeling technique in HEK293T cells under controlled conditions. This dataset encompasses 6,325 proteins that interact with PARP...
ORGANISM(S): Homo sapiens (Human) 
2024-07-15 | PXD052745 | Pride
The mechanisms governing the termination and subsequent reinitiation of RNA polymerase II (Pol II) remain poorly understood. Here we found that depletion of RPB7 leads to the destabilization of Pol II’s largest subunit, RPB1. This destabilization is influenced by the loop regions of RPB7, CDK9, the ...
ORGANISM(S): Mus musculus (Mouse) 
2025-02-05 | PXD048909 | Pride
Quantitative succinyl-proteome profiling of turnip (Brassica rapa var. rapa) in response to cadmium stress.
ORGANISM(S): Brassica rapa var. rapa 
2022-08-11 | PXD028098 | Pride

Large-scale metabolite annotation is a challenge in liquid chromatogram-mass spectrometry (LC-MS)-based untargeted metabolomics. Here, we develop a metabolic reaction network (MRN)-based recursive algorithm (MetDNA) that expands metabolite annotations without the need for a comprehensive standard...

2019-03-26 | MTBLS615 | MetaboLights

With the global prevalence of Varroa mites, more and more beekeepers resort to confining the queen bee in a queen cage to control mite infestation or to breed superior and robust queen bees. However, the impact of such practices on the queen bee remains largely unknown. Therefore, we sub...

2023-09-11 | MTBLS7576 | MetaboLights
The RNA-Seq technique was used to investigate the differentially transcribed genes of the caterpillar fungus Cordyces militaris. It was calculated that >63% of total annotated genes were expressed, including >55% of putative pathogen-host interaction genes. Overall, the fruiting-body development and...
ORGANISM(S): Cordyceps militaris 
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