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Excessive intake of dietary fat is known to be a contributing factor in the development of obesity. In this study, we determined the dose-dependent effects of dietary fat on the development of this metabolic condition with a focus on changes in gene expression in the small intestine. C57BL/6J mice w...
ORGANISM(S): Mus musculus 
The major proteoglycan in cartilage is COMP. This protein undergoes extensive proteolytic turnover that is believed to be dysregulated during osteoarthritis. Here we identify and describe two secreted proteases that are responsible for this turnover and identify the specific sites of proteolysis by ...
ORGANISM(S): Homo sapiens (Human) 
2025-02-26 | PXD057263 | Pride
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