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BALB/c mice are susceptible to proteoglycan (PG) aggrecan-induced arthritis (PGIA), a murine model of rheumatoid arthritis (Glant,T.T. and Mikecz,K., Proteoglycan aggrecan-induced arthritis. A murine autoimmune model of rheumatoid arthritis. Methods Mol.Med. 2004. 102: 313-338.). However, there are...
ORGANISM(S): Mus musculus 
BALB/c mice develop peripheral arthritis (PGIA) and spondyloarthropathy (PGIS) upon repeated intraperitoneal injections of human cartilage proteoglycan (PG) aggrecan. The aim of the present study was to identify spondylitis-specific genes by comparing intervertebral disc (IVD) RNA samples from spond...
ORGANISM(S): Mus musculus 
Enduring Histone Methylation Changes at Proteoglycan Network Genes following Ethanol Exposure
Proteoglycans are distributed in all animal tissues and play critical, multifaceted, physiological roles. Expressed in a spatially- and temporally-regulated manner, these molecules regulate interactions among growth factors and cell surface receptors and play key roles in basement membranes and oth...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) 
2018-05-22 | PXD008855 | Pride
BALB/c mice are susceptible to proteoglycan (PG) aggrecan-induced arthritis (PGIA), a murine model of rheumatoid arthritis (Glant,T.T. and Mikecz,K., Proteoglycan aggrecan-induced arthritis. A murine autoimmune model of rheumatoid arthritis. Methods Mol.Med. 2004. 102: 313-338.). However, there are ...
ORGANISM(S): Mus musculus 
2009-02-15 | GSE13730 | GEO
Proteoglycans (PGs) are proteins with glycosaminoglycan (GAG) chains, such as chondroitin sulfate (CS) or heparan sulfate (HS), attached to serine residues. We have earlier shown that prohormones can carry CS, thus, constituting a novel class of PGs. The mapping of GAG modifications of proteins in e...
ORGANISM(S): Homo sapiens (Human) Mus musculus (Mouse) Rattus norvegicus (Rat) 
2022-02-16 | PXD024230 | Pride
VISTA is an activating receptor that binds the proteoglycan Syndecan-2 on monocytes.
Primary cardiac myocytes isolated from neonatal Wistar rats were cultured and simulated ischemia/reperfusion injury were conducted on them in the presence or absence of decorin. Decorin is a small leucin-rich proteoglycan, which has a cardiocytoprotective effect. The underlaying mechanism of this ca...
ORGANISM(S): Rattus norvegicus 
The proteomic analysis of liver samples from mice administered proteoglycan (PG) for 9 days or untreated control mice. Liver samples from mice administered PG for 9 days or untreated control mice (n = 6 per group) were homogenized in PBS. The proteins were precipitated using acetone. The supernatant...
ORGANISM(S): Mus Musculus (mouse) 
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