The role of regulators of RNA m6A methylation in lung cancer.
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ABSTRACT:
SUBMITTER: Zhang Q
PROVIDER: S-EPMC10201596 | biostudies-literature | 2023 Mar
REPOSITORIES: biostudies-literature
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The role of regulators of RNA m<sup>6</sup>A methylation in lung cancer.
Genes & diseases 20220129 2
N<sup>6</sup>-methyladenosine (m<sup>6</sup>A) modification is found the most prevalent and abundant post-transcriptional mRNA modification in eukaryotic cells. It regulates almost all stages of RNA life cycle including splicing, translocation, stability, decay and translation. As a dynamic and reversible process, m<sup>6</sup>A modification is catalyzed by the RNA methyltransferases ('writers'), removed by the demethylases ('erasers'), and interacts with m<sup>6</sup>A-binding proteins ('reader ...[more]
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