Sort   by:  
 Page size 
MetabolomicsThe effect of the MYH9 in endothelial cells on metabolism

This document focuses on exploring the specific impact of MYH9 on the metabolic processes of vascular endothelial cells. To achieve this, a well-designed experimental approach was adopted: human umbilical vein endothelial cells (HUVECs) were subjected to different treatments using adenoviruses, i...

2026-03-05 | MTBLS12819 | MetaboLights
ProteomicsLong read proteogenomics to characterize protein isoform diversity in human umbilical vein endothelial cells (HUVECs)
Mass spectrometry-based proteomics sample preparation Harvested HUVECs, approximately 5 million cells each, were pelleted and frozen at -80C. The sample pellet was lysed according to the Filter Aided Sample Preparation (FASP) protocol.59 Lysis buffer used in the FASP was changed to 6% SDS, 150 mM DT...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-04-28 | MSV000089326 | MassIVE
MetabolomicsIntegrated Proteomics and Metabolomics Analysis Reveals Differential Lipid Metabolism in HUVEC under high and low shear stress
OBJECTIVE: Atherosclerotic plaque development is closely associated with the hemodynamic forces applied to endothelial cells (EC). Among these, shear stress (SS) plays a key role in disease development since changes in flow intensity and direction could stimulate an atheroprone or athero...
2019-07-25 | MTBLS739 | MetaboLights
ProteomicsLabel-Free Quantitative LC-MS/MS Proteomic Profiling of Human Umbilical Vein Endothelial Cells Treated with Direct Oral Anticoagulants
This dataset contains label-free quantitative (LFQ) LC-MS/MS proteomics data generated from human umbilical vein endothelial cells (HUVECs) treated with therapeutically relevant concentrations of the direct oral anticoagulants (DOACs) apixaban, rivaroxaban, edoxaban, and dabigatran, together with un...
ORGANISM(S): Homo sapiens (Human) 
2026-10-22 | PXD082155 | Pride
Apixaban Q exactive Endothelial cells Rivaroxaban Direct oral anticoagulants Lc-ms/ms Dabigatran Edoxaban Proteome discoverer2.5 Proteomics Lfq Huvec Label-free quantification 
ProteomicsLPS-stimulated endothelial cells using SILAC
Severe sepsis and septic shock, which occur with high incidence and are prevalent in the emergency department setting, are among the most common causes of death in hospitalized patients worldwide, and there has been a continuous increase in the incidence of sepsis of approximately 5–10% per year. En...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-11-10 | MSV000081707 | MassIVE
ProteomicsEndothelial cell proteomic response to Rickettsia conorii infection
Rickettsia conorii is the etiologic agent of Mediterranean spotted fever, a re-emerging disease with significant mortality. This obligate, gram-negative intracellular pathogen is transmitted via tick bites, resulting in disseminated vascular endothelial cell infection with vascular leakage. In the ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-04-01 | MSV000080856 | MassIVE
ProteomicsIntegrated transcriptomic and proteomic analysis of primary human umbilical vein endothelial cells
Human umbilical vein endothelial cells (HUVECs) are a widely-used model system to study many pathological and physiological processes associated with the cardiovascular system. An understanding of genes and proteins that are expressed in any cell type is a fundamental need which facilitates study of...
ORGANISM(S): Homo sapiens (Human) 
2019-04-24 | PXD009687 | Pride
Mass-spectrometry Transcriptome Proteogenomics Splice variants Huvec Proteoform Allelic expression Lc-ms/ms Rna-seq 
ProteomicsThe secretome of cultured human endothelial cells in modelled microgravity
Using chromatography-mass spectrometry on an Ultimate 3000 chromatograph combined with a Maxis 4G mass spectrometer, the secretome of human umbilical vein endothelial cells (HUVEC) cultured under static conditions and modeling microgravity for 24 hours was studied. In the secretome of cells under mi...
ORGANISM(S): Homo sapiens (Human) 
2026-07-01 | PXD013497 | Pride
Endothelial cells Microtubules Rho-gtpases Secretome Chromatography-mass spectrometry 
ProteomicsMulti-omics analysis of endothelial cells reveals the metabolic diversity that underlies endothelial cell functions
Untargeted proteomics dataset of human dermal blood endothelial cells (HDBECs), human umbilical vein endothelial cells (HUVECs), human dermal lymphatic endothelial cells (HDLECs) and intestinal lymphatic endothelial cells (iLECs) in proliferation and quiescence.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2024-11-13 | MSV000096399 | MassIVE
ProteomicsSmall extracellular vesicles secreted by cisplatin-resistant neuroblastoma cells increase lactate secretion and alter metabolic pathways in primary human umbilical vein endothelial cells (HUVECs)
Background: Chemoresistance, particularly to cisplatin, remains a significant challenge in treating high-risk neuroblastoma, resulting in a mere 20% five-year overall survival rate. Tumour-derived small extracellular vesicles (sEVs) have been implicated in cancer progression by promoting angiogenesi...
ORGANISM(S): Homo sapiens (Human) 
2025-11-04 | PXD069251 | Pride
Extracellular vesicles 
Sort   by:  
 Page size