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TranscriptomicsTranscription profiling of human prostate carcinoma cell line PC3 treated with reverse transcriptase inhibitor abacavir
Human prostate carcinoma cell line PC3 was treated with 10mg/ml or 100mg/ml of Abacavir. Gene expression was analyzed on total RNA extracted 48h after treatement. For each condition, 5 indipendent biological replicates were performed
ORGANISM(S): Homo sapiens 
2009-08-15 | E-TABM-532 | biostudies-arrayexpress
TranscriptomicsDifferential adipose tissue gene expression profiles in abacavir treated patients that may contribute to cardiovascular risk: a microarray study
Objective: to compare changes in gene expression by microarray from subcutaneous adipose tissue from HIV treatment naïve patients treated with efavirenz based regimens containing abacavir (ABC), tenofavir (TDF) or zidovidine (AZT). There were significant divergence between ABC and the other two grou...
ORGANISM(S): Homo sapiens 
2015-04-16 | E-GEOD-62117 | biostudies-arrayexpress
ProteomicsKinetics of abacavir-induced remodelling of the Major Histocompatibility Complex class I peptide repertoire
Characterisation of the kinetics of abacavir-induced perturbation of the immunopeptidome of the Major Histocompatibility Complex (MHC) class I molecule HLA-B*57:01.
ORGANISM(S): Homo sapiens (Human) 
2021-05-11 | PXD024331 | Pride
Mhc i antigen presentation Drug hypersensitivity Peptide selection Abacavir T cells Human leukocyte antigen (hla) Immunopeptidome Tapasin 
ProteomicsImpact of abacavir and abacavir analogues on HLA-B*57:01 peptide presentation
Characterisation of peptide ligands of the Major histocompatibility class (MHC) I allele, HLA-B*57:01, expressed in the C1R (Class I reduced) B-lymphoblastoid cell line, after exposure to the anti-retroviral abacavir or abacavir analogues.
ORGANISM(S): Homo sapiens (Human) 
2019-10-03 | PXD015398 | Pride
Lc-msms Hla-b*57:01 Mhc Abacavir Immunopeptidome 
GenomicsAnalysis of human leukocyte antigen (HLA) allotype-specific response in abacavir-exposed keratinocyte
Analysis of human leukocyte antigen (HLA) allotype-specific response in abacavir-exposed keratinocyte
PRJNA433622 | ENA
TranscriptomicsAnalysis of human leukocyte antigen (HLA) allotype-specific response in abacavir-exposed keratinocyte
Abacavir, a nucleoside reverse-transcriptase inhibitor used for the treatment of human immunodeficiency virus (HIV) infection, develops hypersensitivity in patients carrying HLA-B*57:01 allele through drug antigen presentation. We found that abacavir exposure induced HLA allotype-specific innate imm...
ORGANISM(S): Mus musculus 
2018-03-01 | GSE110394 | GEO
GenomicsMus musculus strain:C57BL/6J
Abacavir-induced hypersensitivity project
PRJDB18559 | ENA
Genomics
Microbial diversity of abacavir degrading microbial community
PRJNA1180218 | ENA
UnknownAbacavir pharmacogenetics--from initial reports to standard of care.
Not available
S-EPMC3700656 | biostudies-literature
UnknownStructural Elements Recognized by Abacavir-Induced T Cells.
Not available
S-EPMC5535955 | biostudies-literature
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