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ProteomicsProteomic analysis of the invasiveness of human bladder cancer cells
To identification of key drivers involved in the development of muscle invasive bladder cancer, which displays poor prognosis, we isolated one subpopulation of human 5637 bladder cancer cells with highly invasiveness and the other subpopulation of 5637 cells with low invasiveness by Transwell method...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-27 | MSV000082854 | MassIVE
TranscriptomicsTranscription profiling by array of human T24 bladder cancer cells in response to hypericin-mediated photodynamic therapy in the absence or presence of the p38 MAPK inhibitor PD169316
Study of the gene expression of T24 bladder cancer cells in response to hypericin-mediated photodynamic therapy in the absence or presence of the p38 MAPK inhibitor PD169316
ORGANISM(S): Homo sapiens 
2007-10-01 | E-MEXP-1220 | biostudies-arrayexpress
Proteomicsc-Met activation leads to the establishment of a TGFβ receptor regulatory network required for bladder cancer invasion
Treatment of muscle-invasive bladder cancer remains a major clinical challenge. Aberrant HGF/c-MET upregulation and activation is frequently observed in bladder cancer correlating with cancer progression and invasion. However, the precise mechanisms underlying HGF/c-MET mediated invasion in bladder ...
ORGANISM(S): Homo sapiens (Human) 
2019-08-26 | PXD014736 | Pride
C-met Emt Bladder cancer invasion Phosphorylation Tgfb Smurf2 
ProteomicsIdentification of CDK1 phosphorylation of TFCP2L1 from murine embryonic stem cells and bladder cancer cells
Molecular programs involved in embryogenesis are frequently upregulated in oncogenic dedifferentiation and metastasis. However, their precise roles and regulatory mechanisms remain elusive. Here, we showed that CDK1 phosphorylation of TFCP2L1, a pluripotency-associated transcription factor, orches...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2019-11-08 | PXD015635 | Pride
Pluripotency Cdk1 Stemness features Embryonic stem-cell Bladder cancer 
TranscriptomicsTranscription profiling of human bladder cancer cell line TCCSUP over-expressing the transcription factor Oct-4 and control-tansfected cells
Comparison of TCCSUP cancer cells transformed with an EGFP control vector vs transcription factor Oct-4 overexpressed line of TCCSUP cancer cells
ORGANISM(S): Homo sapiens 
2008-09-30 | E-MEXP-1378 | biostudies-arrayexpress
ProteomicsCharacterization of CD44s glycoproteoforms in bladder tumours and bladder cancer cell culture models
Bladder cancer (BC) is a major health concern retaining high mortality rates when diagnosed at advanced stages. In this context, the clinical management of BC requires the introduction of new biomarkers and molecular targets capable to elicit precision medicine therapeutical approaches. A promising ...
ORGANISM(S): Homo sapiens (Human) 
2022-05-19 | PXD028307 | Pride
Glycosylation Cd44 Glycoproteogenomics Bladder cancer Alternative splicing 
ProteomicsXIAP promotes metastasis of bladder cancer cells by ubiquitylating YTHDC1
X-linked inhibitor of apoptosis protein (XIAP), a member of the IAP family, is overexpressed in a variety of tumors and plays an important role in tumor progression. Increasing evidence suggests that XIAP promotes metastasis of bladder cancer but the underlying mechanism is not very clear. The RNA N...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD055868 | Pride
Bladder cancer invasion/ubiquitylation/xiap/ythdc1/mmp-2 
Genomicsc-Met activation leads to the establishment of a TGFb regulatory network required for bladder cancer invasion
c-Met activation leads to the establishment of a TGFb regulatory network required for bladder cancer invasion
PRJNA413704 | ENA
ProteomicsProteomic analysis of the invasiveness of human bladder cancer cells
To identification of key drivers involved in the development of muscle invasive bladder cancer, which displays poor prognosis, we isolated one subpopulation of human 5637 bladder cancer cells with highly invasiveness and the other subpopulation of 5637 cells with low invasiveness by Transwell method...
ORGANISM(S): Homo sapiens (Human) 
2018-03-15 | PXD007709 | Pride
Tmt6 Invasiveness Human Bladder cancer cells 
TranscriptomicsWhole genome expression data from human urinary bladder cancer
At diagnosis approximately 75% of bladder urothelial carcinomas are non muscle invasive bladder cancers (Ta, T1 and Tis), 20% are muscle invasive bladder cancer (T2-T4) and 5% are already metastatic. Non muscle invasive bladder cancers are characterized by tumor recurrence in 60% to 85% of cases and...
ORGANISM(S): Homo sapiens 
2012-02-22 | E-GEOD-23732 | biostudies-arrayexpress
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