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ProteomicsQuantitative proteomic SILAC analysis of enteroids deleted for Hdac1 or Hdac2
We have exploited organoid SILAC approaches that we have previously developed (A SILAC-Based Method for Quantitative Proteomic Analysis of Intestinal Organoids.- Gonneaud A, Jones C, Turgeon N, Lévesque D, Asselin C, Boudreau F, Boisvert FM. -Sci Rep. 2016 Nov 30;6:38195. doi: 10.1038/srep38195) to ...
ORGANISM(S): Mus musculus (Mouse) 
2019-11-14 | PXD011869 | Pride
Intestin Hdac2 Enteroid Silac Hdac1 
MetabolomicsGNPS - Viequeamides Cyclic Depsipeptides from a Rivularia sp.
Paper title: Viequeamide A, a Cytotoxic Member of the Kulolide Superfamily of Cyclic Depsipeptides from a Marine Button Cyanobacterium Author List: Boudreau PD, Byrum T, Liu WT, Dorrestein PC, Gerwick WH. Citation: J Nat Prod. 2012 Sep 28;75(9):1560-70. DOI: 10.1021/np300321b PubMedID: 22924493 Brie...
ORGANISM(S): Rivularia Sp. 
2014-04-16 | MSV000078594 | GNPS
UnknownLCMS-Metabolomic Profiling and Genome Mining of <i>Delftia lacustris</i> DSM 21246 Revealed Lipophilic Delftibactin Metallophores.
Not available
S-EPMC11472818 | biostudies-literature
ProteomicsLCMS-Metabolomic Profiling and Genome Mining of Delftia lacustris DSMZ 21246 Revealed Four New Delftibactin Metallophores
This dataset encompasses the metabolomic profile of Delftia lacustris DSMZ 21246 cultivated on DMS (iron-limited defined medium). Additionally, as a duplicate, 50% ACN SPE fractions obtained from both high and low supplementation experiments have been incorporated. The dataset also comprises the HPL...
ORGANISM(S): Delftia Lacustris (ncbitaxon:558537) 
2023-12-11 | MSV000093629 | MassIVE
UnknownHepatocyte nuclear factor 4-alpha involvement in liver and intestinal inflammatory networks.
Not available
S-EPMC3886012 | biostudies-literature
TranscriptomicsTranscription profiling of mouse conditional intestinal epithelial Hnf4Ialpha knockout to investigate the role of HNF4alpha in the adult colon
Background & Aims: HNF4α is an important transcriptional regulator of hepatocyte and pancreatic function. Hnf4α deletion is embryonically lethal with severe defects in visceral endoderm formation, liver maturation and colon development. However, the precise role of this transcription factor in ma...
ORGANISM(S): Mus musculus 
2009-01-13 | E-GEOD-11759 | biostudies-arrayexpress
UnknownKIR3DL1/HLA-B Subtypes Govern Acute Myelogenous Leukemia Relapse After Hematopoietic Cell Transplantation.
Not available
S-EPMC5501362 | biostudies-literature
ProteomicsQuantitative Proteomics Identify a Novel DNA Repair-Dependent Role for Hepatocyte Nuclear Factor 4α
Hepatocyte nuclear factor 4 (HNF4) is a transcription factor that acts as a master regulator of genes in several endodermal-derived tissues, including the intestine in which it plays a central role during development and tumorigenesis. To better delineate the mechanisms by which HNF4 can interfere d...
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD008365 | Pride
Gfp-trap Colorectal cancer Dna repair Human Silac Hnf4alpha Quantitative proteomics Bioid 
ProteomicsFunctions of the 12 different isoforms of the hepatocyte nuclear factor 4 alpha (HNF4α)
HNF4α is a nuclear receptor regulating the transcription of genes involved mainly in development, cell differentiation and metabolism. Opposite functions for the two classes of P1 and P2 isoforms of HNF4α have recently been highlighted. These classes include 12 variants of HNF4α that can be expresse...
ORGANISM(S): Homo sapiens (Human) 
2020-04-17 | PXD012146 | Pride
Transcription Proteomics Nuclear receptors Hnf4α Silac Isoforms Colorectal cancer 
UnknownFatigue is associated with poor sleep in people with multiple sclerosis and cognitive impairment.
Not available
S-EPMC3964892 | biostudies-literature
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