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Comparitive proteomics analyses of different cell types of blood i.e. platelets, neutrophils, monocytes and CD4 derived from the Gray platelet syndrome patients and their respective controls using TMT10plex reagents.
ORGANISM(S): Homo sapiens (Human) 
2020-07-23 | PXD016366 | Pride
HDAC6 inhibitors are novel targeted therapies showing good clinical response in a variety of different malignancies. However, their use and farther development is hampered by the limited knowledge regarding what are the endogenous substrates of HDAC6 enzyme. Here we plan to complete acetylome profil...
ORGANISM(S): Homo sapiens (Human) 
2022-11-09 | PXD026010 | Pride
Gray platelet syndrome (GPS) is a rare inherited bleeding disorder characterized by absence of platelet ɑ-granules and pathogenic variants in NBEAL2. To discern the spectrum of pathological features, we obtained genotype and phenotype data from 47 GPS patients and performed RNA sequencing and prot...
ORGANISM(S): Homo sapiens (Human) 
2020-07-28 | PXD017227 | Pride
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