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Impairments in protein glycosylation cause severe developmental disorders and most with prominent neurological involvement. This includes the most abundant GalNAc-type O-glycosylation, but unravelling underlying disease etiologies caused by deficiencies in this glycosylation pathway is hampered by l...
ORGANISM(S): Homo sapiens (Human) 
2025-07-28 | PXD057996 | Pride
Secretory proteins frequently aggregate into non-soluble dense-core granules (DCGs) in recycling endosome-like compartments prior to release. By contrast, aberrantly processed Aβ-peptides derived from Amyloid Precursor Protein (APP) form pathological amyloidogenic aggregations in late-stage Alzheime...
ORGANISM(S): Homo sapiens (Human) 
2025-07-10 | PXD053641 | Pride
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