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ProteomicsStreptomyces sp. MB42 proteomics response to catechin, dopamine, phenylephrine
Streptomyces sp. MB42 produces antimicrobial compound under the pressence of specific compounds. This experiment is to see which gene cluster upregulated during the treatment of target compound.
ORGANISM(S): Streptomyces sp. MBT42 Bacteria 
2022-02-04 | PXD029669 | Pride
Streptomyces sp. mb42 Dopamine Antibiotic Catechin Phenylephrine 
MetabolomicsTranscriptomic and metabolomic data of goat ovarian and uterine tissues during sexual maturation (Ovarian data)

The ovaries and uterus are crucial reproductive organs in mammals, and their coordinated development ensures the normal development of sexual maturity and reproductive capacity. This study aimed to comprehensively capture the different physiological stages of the goat's sexual maturation by selec...

2024-05-30 | MTBLS9794 | MetaboLights
MetabolomicsTranscriptomic and metabolomic data of goat ovarian and uterine tissues during sexual maturation (Uterine data)

The ovaries and uterus are crucial reproductive organs in mammals, and their coordinated development ensures the normal development of sexual maturity and reproductive capacity. This study aimed to comprehensively capture the different physiological stages of the goat's sexual maturation by selec...

2024-05-30 | MTBLS9795 | MetaboLights
ProteomicsProteomics survey of Streptomyces coelicolor strains with natural gross chromosome change
Streptomyces coelicolor normally produce spores with a relatively high heterogeneity, which will produce genetically heterogeneous sub-populations. These sub-populations often exert massive chromosome amplifications and deletions. Cells with gross chromosomal changes produce an increased diversity o...
ORGANISM(S): Streptomyces coelicolor Bacteria 
2020-05-26 | PXD014413 | Pride
Antibiotics over-production Streptomyces coelicolor Bacteria social behavior Chromosome change Division of labour 
MetabolomicsPu-erh tea and theabrownin ameliorate metabolic syndrome in mice via potential microbiota-gut-liver-brain interactions
Metabolic syndrome (MS) is a common metabolic disorder characterized by obesity, insulin resistance, cardiovascular disease and gut microbiota dysbiosis. Pu-erh tea and its ingredient theabrownin have known functions on the reduction of body weight gain and fat accumulation. However, few studies sys...
2024-09-25 | MTBLS2594 | MetaboLights
ProteomicsMetabolic engineering of Streptomyces peucetius for biosynthesis of N,N-dimethylated anthracyclines
Daunorubicin and doxorubicin, two anthracycline polyketides produced by Streptomyces peucetius, are potent anticancer agents that are widely used in chemotherapy, despite severe side effects. Recent advances have highlighted the potential of producing improved derivatives with reduced side effects b...
ORGANISM(S): Streptomyces peucetius subsp. caesius 
2024-01-18 | PXD048604 | Pride
Streptomyces peucetius Lfq Maxquant Qexactive 
UnknownIntegrative Analysis of Pharmacokinetic and Metabolomic Profiles for Predicting Metabolic Phenotype and Drug Exposure Caused by Sotorasib in Rats.
Not available
S-EPMC9017425 | biostudies-literature
ProteomicsAdrenaline-mediated activation of antibiotic production in Streptomyces highlights catechol as elicitor of specialized metabolism
Actinobacteria are a rich source of bioactive molecules, and genome sequencing has shown that the vast majority of their biosynthetic potential has yet to be explored. However, many of their biosynthetic gene clusters (BGCs) are poorly expressed in the laboratory, which prevents discovery of their c...
ORGANISM(S): Streptomyces sp. MBT84 
2022-01-10 | PXD030484 | Pride
Streptomyces Bgcs Antibacteria Mbt84 Catechol 
ProteomicsAdrenaline-mediated activation of antibiotic production in Streptomyces highlights catechol as elicitor of specialized metabolism
Actinobacteria are a rich source of bioactive molecules, and genome sequencing has shown that the vast majority of their biosynthetic potential has yet to be explored. However, many of their biosynthetic gene clusters (BGCs) are poorly expressed in the laboratory, which prevents discovery of their c...
ORGANISM(S): Streptomyces sp. MBT84 
2022-02-04 | PXD030319 | Pride
Streptomyces Bgcs Antibacteria Mbt84 Catechol 
UnknownMetabolic activation of the anti-hepatitis C virus nucleotide prodrug PSI-352938.
Not available
S-EPMC3393470 | biostudies-literature
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