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UnknownImpact of Precision Medicine in Diverse Cancers: A Meta-Analysis of Phase II Clinical Trials.
Not available
S-EPMC4737863 | biostudies-literature
TranscriptomicsTransduction of human fibroblasts with Zic3 combined with OCT4, SOX2 and KLF4 induces stable neural progenitor cell lines
Lineage specific transcription factors (TF) define and reinforce tissue specific cell types. For instance, stable endoderm progenitors were established from human ESC by constitutive expression of SOX7 or SOX17. We hypothesized that combinatorial expression of OCT4, SOX2 and KLF4M-BM- together with ...
ORGANISM(S): Homo sapiens 
2012-05-21 | E-GEOD-29770 | biostudies-arrayexpress
ProteomicsProteome-wide identification of ISG15 sites in HeLa cells
We employed a GlyGly-peptidomics approach to comprehensively map ISG15 modification sites in HeLa cells under three conditions: mock-transfected controls, IFN-induced cells, and cells transfected with the ISGylation machinery. Lysates from wild-type and Isg15 knockout (KO) cells were processed using...
ORGANISM(S): Homo sapiens (Human) 
2026-03-02 | PXD065158 | Pride
Ptm Hela Glygly Isg15 Gg-peptidomics 
ProteomicsMapping ISG15 sites on GAPDH and PGK1 by AP-MS
We employed an AP-MS approach to map ISG15 modification sites on GAPDH and PGK1 in HEK293T cells by overexpression of FLAG-GAPDH, FLAG-PGK1 or FLAG-GFP together with the ISG15 conjugation enzymes (E1, E2, E3) and wild-type HA-ISG15 or conjugation-defective ISG15-AA. Cells were lysed in physiological...
ORGANISM(S): Homo sapiens (Human) 
2026-03-02 | PXD071724 | Pride
Ap-ms Pgk1 Gapdh Isg15 Glycolysis 
TranscriptomicsIdentification of a predictive gene signature to recMAGE A3 antigen-specific cancer immunotherapy in metastatic melanoma and non-small-cell lung cancer
Purpose: To evaluate the presence of a gene expression signature present before treatment as predictive of response to treatment with MAGE‑A3 immunotherapeutic in metastatic melanoma patients and to validate its predictivity in adjuvant therapy of early-stage lung cancer. Patients were participan...
ORGANISM(S): Homo sapiens 
2013-05-30 | E-GEOD-35640 | biostudies-arrayexpress
TranscriptomicsComparative genomic hybridization of 23 human nevi with a pool of primary cutaneous melanoma
Genomic profiles comparing 23 nevi with a pool of primary cutaneous melanoma
ORGANISM(S): Homo sapiens 
2009-04-16 | E-TABM-3 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array on 123 paired tumor and non-tumor tissue samples from patients with non-small cell lung carcinoma to gain a systems biology insight into the current clinical classification
Non-small cell lung cancer (NSCLC), a leading cause of cancer deaths, represents a heterogeneous group of neoplasms, mostly comprising squamous cell carcinoma (SCC), adenocarcinoma (AC) and large-cell carcinoma (LCC). The aim of this study was to gain a systems biology insight into the current clini...
ORGANISM(S): Homo sapiens 
2013-12-11 | E-MTAB-1132 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of cohort of human cutaneous primary melanomas associated with a distant metastasis free survival
Identification of genomic characteristics in a cohorte of human cutaneous primary melanoma associated with a distant metastasis free survival.
ORGANISM(S): Homo sapiens 
2007-04-01 | E-TABM-1 | biostudies-arrayexpress
UnknownAdjuvant Pembrolizumab for Stage IIB or IIC Melanoma: A Secondary Analysis of a Randomized Clinical Trial.
Not available
S-EPMC12914490 | biostudies-literature
UnknownWhat is it like to organize a large-scale educational event for fellow students? A qualitative exploration of student participation in curriculum design.
Not available
S-EPMC8841077 | biostudies-literature
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