Sort   by:  
 Page size 
The ankyrin repeat domain-55 (ANKRD55) gene contains intronic single nucleotide polymorphisms (SNPs) associated with risk to contract multiple sclerosis, rheumatoid arthritis or other autoimmune disorders. Risk alleles of these SNPs are associated with higher levels of ANKRD55 in CD4+ T cells. The b...
ORGANISM(S): Homo sapiens (Human) 
2019-09-25 | PXD013332 | Pride
Proximity-dependent labelling methods are based on promiscuous labeling enzymes that produce reactive molecules that covalently bind neighbor proteins. Labeled proteins can be then purified and identified using affinity-purification coupled to mass spectrometry methods23. Proximity-dependent biotin ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-20 | PXD027759 | Pride
Polycystic liver disease (PLD) is a group of genetic disorders characterized by bile duct dilatation and/or progressive development of multiple intrahepatic fluid-filled biliary cysts (>10), which are the main cause of morbidity. Current surgical and/or pharmacological therapies exert short-term and...
ORGANISM(S): Homo sapiens (Human) Rattus norvegicus (Rat) 
2020-05-25 | PXD017587 | Pride
To study the function of SUMOylation and SUMO-SIM interactions for particular substrates poses several challenges. SUMOylation occurs transiently and often in a small percentage of the total copy numbers of a given substrate. Modified proteins can be readily deSUMOylated and SUMO can be recycled and...
ORGANISM(S): Homo sapiens (Human) 
2021-09-21 | PXD021923 | Pride
The proteomic profiling of serum samples supposes a challenge due to the large abundance of few blood proteins in comparison with other circulating proteins coming from different tissues and cells. Although the sensitivity of protein detection has increased enormously in the last years, to enrich le...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD029015 | Pride
Titanium is widely used in bone prostheses due to its excellent biocompatibility and osseointegration capacity. To understand the effect of sandblasted acid-etched (SAE) Ti implants on the biological responses of human osteoblast (HOb), their proteomic profiles were analysed using nLC-MS/MS. The cel...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD035986 | Pride
Sort   by:  
 Page size