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ProteomicsTop-down analysis of histone proteins from asynchronous chlamydomonas
These are salt-and-acid histone extracts from asynchronously grown Chlamydomonas measured by LC-MS/MS via top-down analysis. These 5 runs are biological repeats used in our JASMS 2021 paper (Rommelfanger et al.).
ORGANISM(S): Chlamydomonas Reinhardtii (ncbitaxon:3055) 
2021-11-26 | MSV000088458 | MassIVE
TranscriptomicsMembers of the Entamoeba histolytica transmembrane kinase family play non-redundant roles in growth and phagocytosis
Entamoeba histolytica contains a large and novel family of transmembrane kinases (TMK) with proposed roles that include both amebic response to the environment and immune evasion. In the later case, the process requires several elements --these include a large gene family encoding antigenically dist...
ORGANISM(S): Entamoeba histolytica 
2010-11-01 | E-GEOD-19064 | biostudies-arrayexpress
UnknownPB2099: A FIRST-IN-HUMAN PHASE 1 TRIAL OF NX-1607, A FIRST-IN-CLASS ORAL CBL-B INHIBITOR, IN PATIENTS WITH ADVANCED MALIGNANCIES INCLUDING RICHTER TRANSFORMATION DLBCL
Not available
S-EPMC9431483 | biostudies-literature
UnknownCRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer's PSEN2 N141I neurons.
Not available
S-EPMC5660456 | biostudies-literature
MetabolomicsBotanical collections as an opportunity to explore nature through the time: An untargeted metabolomic study in historical and modern Nicotiana leaves

The living and dried specimens in botanical collections play an important role in society for scientific and recreational purposes, offering the opportunity to obtain both macroscopic and molecular information for individual plants, ecosystems, and environmental studies. Untargeted metabolomics i...

2024-03-06 | MTBLS4564 | MetaboLights
UnknownComparison of Joint and Landmark Modeling for Predicting Cancer Progression in Men With Castration-Resistant Prostate Cancer: A Secondary Post Hoc Analysis of the PREVAIL Randomized Clinical Trial.
Not available
S-EPMC8207237 | biostudies-literature
ProteomicsBrown bear skeletal muscle quantitative LC-MSMS
Muscle atrophy is one of the main deleterious consequences of ageing and physical inactivity. Although basic knowledge regarding the underlying mechanisms of muscle atrophy is continuously growing, there are still no efficient therapeutic strategies for its prevention and treatment. Hibernating bear...
ORGANISM(S): Ursus arctos (Brown bear) (Grizzly bear) 
2019-05-14 | PXD004908 | Pride
Lc-msms Skeletal muscle Hibernation Bears 
ProteomicsBrown bear skeletal muscle 2D-DIGE-LC-MSMS
Muscle atrophy is one of the main deleterious consequences of ageing and physical inactivity. Although basic knowledge regarding the underlying mechanisms of muscle atrophy is continuously growing, there are still no efficient therapeutic strategies for its prevention and treatment. Hibernating bear...
ORGANISM(S): Ursus arctos arctos (European brown bear) 
2019-05-14 | PXD011687 | Pride
Lc-msms Skeletal muscle Hibernation Bears 2d-dige 
ProteomicsQuantitative proteomics of brown bear muscle during hibernation
During hibernation, the physiology of bears is characterized by strong metabolic depression. In skeletal muscles, lipids are used as the main energy fuels although their oxidation rate is reduced, and glycolysis appears maintained likely feeding the Cori cycle. For a better knowledge on proteome rem...
ORGANISM(S): Ursus arctos (Brown bear) (Grizzly bear) 
2026-03-02 | PXD060503 | Pride
Lc-msms Metabolic depression Bear Hibernation Muscle 
ProteomicsLC-MSMS analysis of bear muscle mitochondria during hibernation
During hibernation, the physiology of bears is characterized by strong metabolic depression. In skeletal muscles, lipids are used as the main energy fuels although their oxidation rate is reduced, and glycolysis appears maintained likely feeding the Cori cycle. Mitochondria no doubt play an essentia...
ORGANISM(S): Ursus arctos arctos (European brown bear) 
2026-03-02 | PXD036916 | Pride
Lc-msms Metabolic depression Temperature Bear Hibernation 
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