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MetabolomicsNi-MOFs as a Simple and Effective Nanomedicine for ROS-Mediated Antibacterial Wound Healing via a Themoelectrocatalytic Process

Thermoelectrocatalytic nickel-based metal-organic frameworks (Ni-MOFs) autonomously generate reactive oxygen species (ROS) via human body-ambient temperature differences. They exhibit potent antibacterial activity against wound-infecting pathogens, and effectively promote infected skin wound heal...

2026-03-13 | MTBLS14045 | MetaboLights
MetabolomicsThe mechanism of vascular injury caused by polystyrene microplastics: A molecular toxicology study involving ferroptosis and metabolomics

Background: Polystyrene microplastics (PS-MPs) are degradation products of plastics that are prevalent in the environment. Recent studies have established a significant correlation between exposure to PS-MPs and the incidence of cardiovascular diseases (CVD). Objective: This study aims to investi...

2026-08-16 | MTBLS14514 | MetaboLights
MetabolomicsGNPS-Metabolism of drug and dietary substrates by synthetic human fecal microbiome (hCom)
Incubation of drug and dietary substrates with human synthetic community of fecal microbiome. Sample were incubated for 72 hrs in BHI media with/without the dietary substrates and analyzed using Exploris240.
ORGANISM(S): Human Synthetic Community 
2025-07-15 | MSV000098525 | GNPS
MetabolomicsGNPS-Metabolism of drug and dietary substrates by human SynCom
Incubation of drug and dietary substrates with human synthetic community of fecal microbiome. Sample were incubated for 72 hrs in BHI media with/without the dietary substrates and analyzed using Exploris240.
ORGANISM(S): Hcom 
2025-07-24 | MSV000098638 | GNPS
ProteomicsIdentification of receptor-binding domains of Bacteroidales antibacterial pore-forming toxins
Bacteroidales are abundant Gram-negative bacteria present in the gut microbiota of most animals, including humans, where they carry out vital functions for host health. To thrive in this competitive environment, Bacteroidales use sophisticated weapons to outmatch competitors. Among these, BSAPs (Bac...
ORGANISM(S): Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482) 
2025-11-29 | PXD062775 | Pride
Lc-msms Bacteroides fragilis Bsap receptor Co-purification Membrane fraction 
ProteomicsCardiovirus-Mediated PKR Inhibition Results from Nucleocytoplasmic Trafficking Disruption
Protein kinase R (PKR) is a key antiviral kinase activated by binding double-stranded RNA (dsRNA) produced during viral replication. Upon activation, PKR phosphorylates eIF2α, leading to the inhibition of translation and viral replication. However, many viruses have evolved mechanisms to counteract ...
ORGANISM(S): Homo sapiens (Human) 
2025-11-17 | PXD066206 | Pride
Nucleocytoplasmic traffic Pkr Nucleocytoplasmic trafficking disorder (nctd) Cardiovirus Stress granules. Picornavirus Nucleoli Double-stranded rna Eif2ak2 
MetabolomicsMicrobial metabolism driven by nanobiohybrids via electromagnetic induction
Microorganisms sustain biogeochemical cycles via metabolically driven redox reactions that require essential external energy. Beyond conventional chemotrophy and phototrophy, many microorganisms remain metabolically active under extreme energy limitation, suggesting the existence of alternative ener...
2026-06-09 | MTBLS14722 | MetaboLights
ProteomicsLCMS spermatozoa and seminal plasma
This dataset contains raw and processed LC–MS/MS data from a paired proteomic analysis of seminal plasma and spermatozoa fractions obtained from the same ejaculates of two adult stallions. Samples were analyzed using a Vanquish nanoLC system coupled to an Orbitrap Exploris 240 mass spectrometer oper...
ORGANISM(S): Equus caballus (Horse) 
2026-05-21 | PXD074771 | Pride
Seminal plasma Exploris240 Ecuus qabalus Spermatozoa 
MetabolomicsThe effect of transplanted mouse feces on serum metabolites of recipient mice after ionizing radiation irradiation
Collect feces from mice exposed to ionizing radiation at 1 week, 2 weeks, 3 weeks, and 4 weeks respectively. After treatment with compound antibiotics, transplant the feces of mice irradiated with ionizing radiation, collect serum from recipient mice, and detect the content of metabolites.
2026-09-28 | MTBLS15756 | MetaboLights
ProteomicsDeep plasma proteomics with data-independent acquisition: A fastlane towards biomarkers identification
Plasma proteomic is a precious tool in human disease research, but requires extensive sample preparation in order to perform in-depth analysis and biomarker discovery using traditional Data-Dependent Acquisition (DDA). Here, we highlight the efficacy of combining moderate plasma prefractionation and...
ORGANISM(S): Homo sapiens (Human) 
2024-09-24 | PXD047901 | Pride
Dia-nn Data-independent acquisition Deep proteome analysis Plasma proteomics Fractionation Clinical proteomics Covid-19 Biomarkers 
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