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ProteomicsMultiplexed proteome dynamics profiling of HSP90 inhibitor 17-AAG in anti-CD3 and anti-CD28 stimulated T-cells
Investigation of proteostatic effects of HSP90 inhibition by 17-AAG and differentiation of maturation state dependent HSP90 requirements of proteins in activated T-cells.
ORGANISM(S): Homo sapiens (Human) 
2018-05-02 | PXD008634 | Pride
Hsp90 Anti-cd28 Activated t-cells 17-aag Mpdp Primary t-cells Anti-cd3 
ProteomicsMultiplexed proteome dynamics profiling of Estradiol and SERMs
Investigation of proteostatic effects of Estradiol, raloxifen and GW7604 in MCF7 cells.
ORGANISM(S): Homo sapiens (Human) 
2018-05-02 | PXD008636 | Pride
Gw7604 Mpdp Raloxifen Estradiol 
ProteomicsMultiplexed proteome dynamics profiling of HSP90 inhibitor 17-AAG in T-cells
Investigation of proteostatic effects of HSP90 inhibition by 17-AAG and differentiation of maturation state dependent HSP90 requirements of proteins in resting T-cells.
ORGANISM(S): Homo sapiens (Human) 
2018-05-02 | PXD008635 | Pride
Hsp90 17-aag Mpdp Primary t-cells 
ProteomicsMultiplexed proteome dynamics profiling of HSP90 inhibitor 17-AAG
Investigation of proteostatic effects of HSP90 inhibition by 17-AAG and differentiation of maturation state dependent HSP90 requirements of proteins.
ORGANISM(S): Homo sapiens (Human) 
2018-04-05 | PXD008633 | Pride
Hsp90 17-aag Mpdp 
ProteomicsMultiplexed proteome dynamics profiling of JQ1-PROTAC
Goal of this experiment was the differentiation of direct targets of induced degradation of the JQ1-PROTAC from downstream regulatory effects.
ORGANISM(S): Homo sapiens (Human) 
2018-05-02 | PXD008637 | Pride
Vhl Protac Mpdp Jq1 
ProteomicsThermal proteome profiling of JQ1
Goal of this experiment was the identification of proteins affected in their thermal stability by JQ1.
ORGANISM(S): Homo sapiens (Human) 
2018-05-02 | PXD008638 | Pride
Jq1 Tpp 
ProteomicsT-cell protein half live - Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis
Determine half lives of proteins in T-cells using dynamic SILAC labeling
ORGANISM(S): Homo sapiens (Human) 
2018-05-02 | PXD008630 | Pride
Dynamics silac Turnover Half live 
ProteomicsJurkat protein half live - Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis
Determine half lives of proteins in Jurkat using a dynamic SILAC labeling
ORGANISM(S): Homo sapiens (Human) 
2018-04-06 | PXD008629 | Pride
Dynamics silac Turnover Half live 
ProteomicsExpression proteomics combination treatment of Estradiol and SERMs
Investiagte antagonistic effects of modulators vs. Activator of ESR1 in co-treated cells
ORGANISM(S): Homo sapiens (Human) 
2018-05-02 | PXD008628 | Pride
Gw7604 Mpdp Raloxifen Estradiol 
ProteomicsThermal proteome profiling of Jurkat cells
Determine melting temperature of proteins in Jurkats
ORGANISM(S): Homo sapiens (Human) 
2018-05-02 | PXD008639 | Pride
Jurkat Tpp 
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