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UnknownUsing FASS-LTP in postmortem mice brain tissues to assess pathological synaptic function.
Not available
S-EPMC12940509 | biostudies-literature
ProteomicsPDGF-hSyn Synaptosomes (vGlut FASS) nanoLC-MS/MS
This project studies the differential abundance of proteins at excitatory synapses of PDGF-hSyn mice (Masliah et al., 2000, Science), which are a model for Parkinson’s disease/dementia with Lewy bodies. The mice overexpress human alpha synuclein under the human PDGF promoter. Synapses were purified ...
ORGANISM(S): Mus musculus (Mouse) 
2019-09-02 | PXD006812 | Pride
Vglut Lewy body Synaptosome Excitatory synapse Parkinson’s diseas 
ProteomicsThe proteomic landscape of synaptic diversity across brain regions and cell types
Brain function relies on communication via neuronal synapses. Neurons build and diversify synaptic contacts using different protein combinations that define the specificity, function and plasticity potential of synapses. More than a thousand proteins have been globally identified in both pre- and po...
ORGANISM(S): Mus musculus (Mouse) 
2023-11-30 | PXD039946 | Pride
Synapse Fass Synaptosomes 
UnknownForce analysis of slope reinforced by Frame-Anchor-Support-Structure based on improved horizontal slice method.
Not available
S-EPMC11805443 | biostudies-literature
UnknownLiquid Plasticine-Based Electrokinetic Enrichment of Proteins.
Not available
S-EPMC10041546 | biostudies-literature
ProteomicsCross-linking of mouse laminin 111
Laminin, a ~800 kD heterotrimeric protein, is a major functional component of the extracellular matrix, contributing to tissue development and maintenance. We used cross-linking and mass spectrometry to determine the order of subunits in the ~750 Å trimeric coiled-coil oligomerization domain of lami...
ORGANISM(S): Mus musculus (Mouse) 
2016-12-22 | PXD004898 | Pride
Cross linking Extra cellular matrix Laminin 
TranscriptomicsTranscriptome profiling of leaves in two genotypes of perennial ryegrass during cold acclimation
The changes in the transcriptome of leaves between 0, 9, 13 and 17 days of cold acclimation were analyzed using RNA-Seq in Veyo and Falster genotypes of perennial ryegrass.
ORGANISM(S): Lolium perenne 
2016-04-20 | E-MTAB-2779 | biostudies-arrayexpress
UnknownLipid Dynamics, Identification, and Expression Patterns of Fatty Acid Synthase Genes in an Endoparasitoid, Meteorus pulchricornis (Hymenoptera: Braconidae).
Not available
S-EPMC7503466 | biostudies-literature
ProteomicsExtracellular Matrix proteomics
Proteomics of extracellular matrix from fibroblast cell cultures (WI-38). The results of these experiments were used to supprt an electron microscopy study of the extracellular matrix.
ORGANISM(S): Homo sapiens (Human) 
2019-03-13 | PXD007700 | Pride
Extracellular matrix Ecm 
TranscriptomicsRNA-seq of WTAP knockdown human pluripotent stem cells during the exit from pluripotency induced by Activin/Nodal inhibition
This experiment was designed to monitor the gene expression changes induced by the knockdown of WTAP in human pluripotent stem cells (hPSCs) during the exit from pluripotency induced by the inhibition of Activin/Nodal signalling. hPSCs carrying a tetracycline-inducible short hairpin RNA (shRNA) agai...
ORGANISM(S): Homo sapiens 
2018-01-04 | E-MTAB-5230 | biostudies-arrayexpress
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