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ProteomicsComparative Proteomics of Hepatic Mitochondrial Subpopulations During MASH Progression
Proteomics profiling of enriched Cytoplasmic and Peridroplet mitochondria from healthy and diet-induced MASLD/MASH mouse models
ORGANISM(S): Mus musculus (Mouse) 
2025-01-20 | PXD052526 | Pride
Mouse Liver Mitochondria Mash 
ProteomicsProteomics of Pulmonary alveolar microlithiasis nodules
The proteomics aspect of this project was simply to catalog the protein content in microlith nodule isolated from a Pulmonary alveolar microlithiasis patient or from a mouse model of the disease
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD039280 | Pride
Lc-msms Pulmonary alveolar microlithiasis (pam) Lung Proteomics 
ProteomicsMultiplex Biomarker Screening Assay for Urinary Extracellular Vesicles Study: A Targeted Label-Free Proteomic Approach
The recent advance in targeted label-free proteomics, SWATH-MS, can provide consistent protein detection and reproducible protein quantitation, which is a considerable advantage for biomarker study of urinary exosome-enriched extracellular vesicles (EVs). We developed a SWATH-MS workflow with a cura...
ORGANISM(S): Homo sapiens (Human) 
2018-10-11 | PXD008891 | Pride
Biomarker  exosomes  human urine  microvesicles  post-acquisition data extraction  proteome 
ProteomicsSWATH-proteomics analysis of ibrutinib mechanism of action in neutropenia and acute myeloid leukemia initiating mutated granulocyte-colony stimulating factor receptor
Neutrophil production and function are primarily determined by granulocyte colony stimulating factor receptor (G-CSFR). G-CSFRs associated mutations (mostly localized in the transmembrane and cytoplasmic domains of the receptor) have been reported with several distinct hematological abnormalities as...
ORGANISM(S): Mus musculus (Mouse) 
2020-04-27 | PXD013402 | Pride
Btk inhibitor Swath 32d G-csfr 
ProteomicsPhosphoproteomics analysis of normal and mutated granulocyte colony stimulating factor receptors
Granulocyte colony stimulating factor receptor (G-CSFR) plays important role in the production of neutrophils from hematopoietic stem cells. Mutated form of the receptor has been directly associated with two distinct malignant phenotype in patients, e.g. acute myeloid leukemia (AML) and chronic neut...
ORGANISM(S): Mus musculus (Mouse) 
2019-02-14 | PXD009311 | Pride
Phosphoproteomics Silac G-csfr signaling 
ProteomicsSystematic Evaluation of Data-Independent Acquisition for Sensitive and Reproducible Proteomics – a Prototype Design for a Single Injection Assay
This dataset includes twelve DIA methods with various mass-isolation windows that analyze precursor ranges from 400-1250 m/z as well as shotgun acquired data with the same instrument and LC gradient. The mass-isolation windows analyzed included 3, 6, and 26 m/z widths. Each 3 m/z window method ana...
ORGANISM(S): Escherichia coli 
2015-12-02 | PXD002688 | Pride
Protalizer  dia  swath  pacific  label-free quantification 
ProteomicsSWATH-MS Analysis of Gfi1-mutant bone marrow neutrophils
This study investigates the proteomic alterations in bone marrow neutrophils isolated from 5-8 week old Gfi1+/-, Gfi1K403R/-, Gfi1R412X/-, and Gfi1R412X/R412X mice using the SWATH-MS technique. This dataset consists of 26 raw MS files, comprising 13 DDA (for spectral library generation)and 13 DIA (f...
ORGANISM(S): Mus musculus (Mouse) 
2020-04-07 | PXD010943 | Pride
Scn Gfi1 Swath Neutrophil 
MetabolomicsGNPS - Insights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis
Pulmonary alveolar microlithiasis is an autosomal recessive lung disease caused by a deficiency in the pulmonary epithelial Npt2b sodium-phosphate co-transporter that results in accumulation of phosphate and formation of hydroxyapatite microliths in the alveolar space. The single cell transcriptomic...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-02-16 | MSV000091302 | GNPS
ProteomicsInsights into pulmonary phosphate homeostasis and osteoclastogenesis emerge from the study of pulmonary alveolar microlithiasis
Pulmonary alveolar microlithiasis is an autosomal recessive lung disease caused by a deficiency in the pulmonary epithelial Npt2b sodium-phosphate co-transporter that results in accumulation of phosphate and formation of hydroxyapatite microliths in the alveolar space. The single cell transcriptomic...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2023-02-16 | MSV000091302 | MassIVE
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