Sort   by:  
 Page size 
TranscriptomicsTranscription profiling of human newly diagnosed T-ALL patients treated in the Childrens Oncology Group (COG) T-ALL Study 9404
The clinical and cytogenetic features associated with T-cell acute lymphoblastic leukemia (T-ALL) are not predictive of early treatment failure. Based on the hypothesis that microarrays might identify patients who fail therapy, we used the Affymetrix U133 Plus 2.0 chip and prediction analysis of mic...
ORGANISM(S): Homo sapiens 
2009-02-07 | E-GEOD-14618 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human T-ALL (COG study 9404)
The clinical and cytogenetic features associated with T-cell acute lymphoblastic leukemia (T-ALL) are not predictive of early treatment failure. Based on the hypothesis that microarrays might identify patients who fail therapy, we used the Affymetrix U133 Plus 2.0 chip and prediction analysis of mic...
ORGANISM(S): Homo sapiens 
2009-02-09 | E-GEOD-14615 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human T-ALL patients (COG study 8704)
The clinical and cytogenetic features associated with T-cell acute lymphoblastic leukemia (T-ALL) are not predictive of early treatment failure. Based on the hypothesis that microarrays might identify patients who fail therapy, we used the Affymetrix U133 Plus 2.0 chip and prediction analysis of mic...
ORGANISM(S): Homo sapiens 
2009-02-09 | E-GEOD-14613 | biostudies-arrayexpress
ProteomicsAn integrated multi-omic workflow reveals markers of host-microbe dynamics in clinical cystic fibrosis samples
Airway microbiota composition correlates with cystic fibrosis (CF) progression, however, microbial drivers of disease remain unclear. MS-based metaproteomics of bronchoalveolar lavage fluid (BALF) offers insights into both host and microbe dynamics and potential interactions. However, detection of...
ORGANISM(S): Homo sapiens (Human) 
2024-06-25 | PXD041457 | Pride
Human Faims Cystic fibrosis Bronchoalveolar lavage Bal Cf Prm Immune Microbe Mass spectrometry Lung Infection 
ProteomicsXL-MS Analysis of Recombinant GPR158:RGS7:Gb5 Complex in Detergent Micelles
GPR158 is widely expressed in the brain and have been implicated in depression, cognition, mood and several cancers. GPR158 is also involved in retinal photoreceptor signaling along with it involvement in synaptic organization. GPR158 interact with G-protein regulator-RGS7 and brings it to plasma me...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD026603 | Pride
Rgs7 Orphan gpcr Gb5 Gpcr-rgs complex Membrane protein complex Gpr158 G-protein coupled receptor Chemical crosslinking 
ProteomicsStructural insights into IMP2 dimerization and RNA binding
IGF2BP2 (IMP2) is an RNA binding protein contributing to tumorigenesis across various cancers as well as to metabolic disorders. With the growing interest in drug discovery efforts targeting IMP2, an understanding of its structural properties and biological behavior are needed. Thus far, only partia...
ORGANISM(S): Homo sapiens (Human) 
2026-05-25 | PXD049065 | Pride
Imp2 Hdx-ms 
ProteomicsHDX-MS Analysis of RORg:RORE:SRC3 Complexes
The retinoic acid receptor-related orphan receptor γ (RORγ) is a ligand-dependent transcription factor that both underpins metabolic and immune functions and provides vantage to manipulate those processes pharmacologically. Despite its importance, our understanding of the ligand-dependent activities...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD025765 | Pride
Protein-dna interaction Rorg Rorg response elements Hydrogen deuterium exchange mass spectrometry Protein-protein interaction Src3 
ProteomicsData-Independent Acquisition Mass Spectrometry as a Tool for Metaproteomics: Interlaboratory Comparison Using a Model Microbiome
Metaproteomics used bottom-up mass spectrometry to detect and quantify the proteins present in microbiome samples. Historically, the methodology of choice in these analyses has been Data-Dependent Acquisition mass spectrometry (DDA-MS). In this manuscript we see sought to evaluate the reproducibilit...
ORGANISM(S): Enterobacteria phage ES18 Thermus thermophilus Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) Bacteria Stenotrophomonas maltophilia Nitrosospira multiformis Anthracocystis tumefaciens Alteromonas macleodii Archaea Salmonella phage P22 Paracoccus denitrificans Pseudomonas denitrificans (nom. rej.) unclassified Bacillus subtilis group Roseobacter Cupriavidus metallidurans Chlamydomonas reinhardtii Nitrososphaera viennensis Enterobacteria phage f2 Nitrosomonas ureae Escherichia phage M13 Chromobacterium violaceum unclassified Pseudomonas fluorescens group Escherichia coli Pseudomonas cf. pseudoalcaligenes Rhizobium leguminosarum Desulfovibrio vulgaris str. Hildenborough Staphylococcus aureus Paraburkholderia xenovorans 
2024-12-19 | PXD054415 | Pride
Data independent acquisition Microbiome Metaproteomics 
ProteomicsMetaproteomic analysis of nasopharyngeal swab samples to identify microbial peptides and potential co-infection status in COVID-19 patients
Respiratory infections disrupt the microbiota in the upper respiratory tract (URT), putting patients at a risk for subsequent infections. During the pandemic, cases of COVID-19 were aggravated by secondary infections because of impaired immunity and medical interventions, which was clearly evident i...
ORGANISM(S): Homo Sapiens 
2025-11-01 | PXD039598 | panorama
ProteomicsCritical Assessment of Metaproteome Investigation (CAMPI): a Multi-Lab Comparison of Established Workflows
Metaproteomics, the study of the collective proteome within a microbial ecosystem, has substantially grown over the past few years. This growth comes from the increased awareness that it can powerfully supplement metagenomics and metatranscriptomics analyses. Although metaproteomics is more challeng...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) Homo Sapiens (ncbitaxon:9606) 
2022-06-08 | MSV000089620 | MassIVE
Sort   by:  
 Page size