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ProteomicsThe glycosaminoglycan-dependent interactome of neurexin-1 in human fetal glial cells
Neurexins are synaptic adhesion molecules best characterized in neurons, where they regulate synapse assembly and function, with emerging evidence indicating they are also abundantly expressed by astrocytes. To elucidate the interactome of NRXN1α, we employed a proximity labeling strategy in culture...
ORGANISM(S): Homo sapiens (Human) 
2025-12-22 | PXD069099 | Pride
Proximity tagging Glycosaminoglycan Interactome Thrombospondin-1 Neurexin-1 
ProteomicsAPEX-Gal1 Labeled C2C12 Myoblasts
Myogenic differentiation is influenced by interactions at the cell surface involving the glycan binding protein galectin-1. Using a proximity labeling galectin-1 construct, we biotinylated and enriched galectin-1 interactors in mouse myoblasts, and analyzed them by LC/MS/MS to determine relevant gal...
ORGANISM(S): Mus musculus (Mouse) 
2021-07-05 | PXD026718 | Pride
Mouse Lc/msms Myoblasts 
ProteomicsMapping the placental galectin-3 interactome identifies CD9 and ITGB1 as functional glycoprotein counter-receptors during syncytialization.
The fetomaternal interface is replete with glycan-binding proteins (GBPs) that can interact with cell surface glycoprotein counter-receptors to regulate placental function. Here, we interrogate the role of galectin-3, a GBP that controls placental trophoblast syncytialization, an important different...
ORGANISM(S): Homo sapiens (Human) 
2025-11-24 | PXD069219 | Pride
Glycosylation Trophoblast Proximity labeling Tetraspanin Mass spectrometry (ms)-based proteomics Syncytialization Galectin-3 Glycan-binding protein 
ProteomicsMapping glycan-mediated galectin-3 interactions by live cell proximity labeling
Galectin-3 is a glycan-binding protein (GBP) that binds β -galactoside glycan structures to orchestrate a variety of important biological events, including the activation of hepatic stellate cells and regulating immunological responses. While the requisite glycan epitopes needed to bind galectin-3 h...
ORGANISM(S): Homo sapiens (Human) 
2021-06-16 | PXD021622 | Pride
Proteomics Galectins Proximity labeling 
ProteomicsCharting the dynamic trophoblast plasma membrane identifies LYN as a functional regulator of syncytialization (supplemental)
The differentiation of placental cytotrophoblasts (CTBs) into the syncytiotrophoblast (STB) layer results in significant remodeling of the plasma membrane proteome. Here, we use a peroxidase-catalyzed proximity labeling strategy to quantitatively map the dynamic plasma membrane proteomes of CTBs and...
ORGANISM(S): Homo sapiens (Human) 
2025-10-02 | PXD055086 | Pride
Placenta Syncytialization Plasma membrane Surfaceome 
GenomicsGenome-wide maps of cytosine methylation, cytosine hydroxylmethylation and small non coding RNAs in mouse ES cells and upon guided differentiation to mesoendoderm cells
Genome-wide maps of cytosine methylation, cytosine hydroxylmethylation and small non coding RNAs in mouse ES cells and upon guided differentiation to mesoendoderm cells. Mouse embryonic stem cells (E14) were guided differentiated into mesoendoderm lineages by activin-A induction. cells in three time...
ORGANISM(S): Mus musculus 
2012-09-22 | E-GEOD-38596 | biostudies-arrayexpress
UnknownEmpagliflozin in Patients with Chronic Kidney Disease.
Not available
S-EPMC7614055 | biostudies-literature
UnknownRobust estimation of bacterial cell count from optical density.
Not available
S-EPMC7499192 | biostudies-literature
UnknownRelationship Between Preexisting Cardiovascular Disease and Death and Cardiovascular Outcomes in Critically Ill Patients With COVID-19.
Not available
S-EPMC9575399 | biostudies-literature
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