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ProteomicsTetraspanin-based immunocapture for high-depth proteomic profiling of extracellular vesicles from cerebrospinal fluid for biomarker discovery
Due to its proximity to cells of the central nervous system, cerebrospinal fluid (CSF) is an important source of novel biomarkers for neurological diseases. Membrane-bound extracellular vesicles (EVs) are enriched for proteins of intracellular and membrane origin, implicated in the pathogenesis of s...
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD061653 | Pride
Cerebrospinal fluid Proteomics Tetraspanin Extracellular vesicle Immunocapture. 
ProteomicsProteomic profiling of KIT-containing EVs secreted by neoplastic human mast cells (SUB1)
Activating mutations in the receptor KIT promote the dysregulated proliferation of human mast cells (huMCs). The resulting neoplastic huMCs secrete extracellular vesicles (EVs) that can transfer oncogenic KIT among other cargo into recipient cells. Despite potential contributions to diseases, KIT-co...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD033889 | Pride
Exosomes Microvesicles Extracellular vesicles Kit Immunocapture Mast cell 
ProteomicsProteomic profiling of KIT-containing EVs secreted by neoplastic human mast cells (SUB2)
Activating mutations in the receptor KIT promote the dysregulated proliferation of human mast cells (huMCs). The resulting neoplastic huMCs secrete extracellular vesicles (EVs) that can transfer oncogenic KIT among other cargo into recipient cells. Despite potential contributions to diseases, KIT-co...
ORGANISM(S): Homo sapiens (Human) 
2025-12-02 | PXD033890 | Pride
Exosomes Microvesicles Extracellular vesicles Kit Immunocapture Mast cell 
ProteomicsExploring Diverse Clinical Presentations in COVID-19 through Circulating Extracellular Vesicle Proteomics Analysis
Extracellular vesicles (EVs) released by virus-infected cells are susceptible to incorporate viral peptides. Here, we hypothesized that the molecular characterization of EVs obtained from COVID-19 patients will reveal novel immunogenic viral peptides. Blood from COVID-19 patients with severe (G1), m...
ORGANISM(S): Homo sapiens (Human) Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2024-09-25 | PXD041931 | Pride
Proteomics profiling Covid-19 patients Clinical data Ganglioside-capture(siglec-1) Antibody response Extracellular vesicles Size-exclusion chromatography(sec) Tandem mass tag(tmt) Immunocapture(cd9) 
UnknownGamma-glutamyltransferase activity in exosomes as a potential marker for prostate cancer.
Not available
S-EPMC5420129 | biostudies-literature
UnknownCharacterization of Extracellular Vesicles from Human Saliva: Effects of Age and Isolation Techniques.
Not available
S-EPMC10778510 | biostudies-literature
UnknownLiquid Biopsy in Organ Damage: small extracellular vesicle chip-based assessment of polytrauma.
Not available
S-EPMC10684673 | biostudies-literature
UnknownProstate cancer sheds the αvβ3 integrin in vivo through exosomes.
Not available
S-EPMC6541230 | biostudies-literature
UnknownHigh sensitivity detection of extracellular vesicles immune-captured from urine by conventional flow cytometry.
Not available
S-EPMC6376115 | biostudies-literature
UnknownProteomics of circulating extracellular vesicles reveals diverse clinical presentations of COVID-19 but fails to identify viral peptides.
Not available
S-EPMC11576438 | biostudies-literature
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