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ProteomicsHuman chorionic gonadotropin promotes murine Treg cells and restricts pregnancy-harmful proinflammatory Th17 responses – proteomics data
In this study, the participation of fetal factors in maintaining the immune balance during gestation was investigated by assessing the effects of human chorionic gonadotropin (hCG) on murine Treg cells and Th17 cells.
ORGANISM(S): Mus musculus (Mouse) 
2022-10-14 | PXD035883 | Pride
Mouse Th17 cells Lfq Fetus Hcg Treg cells 
ProteomicsEffects of contact allergens on THP-1 cells – LFQ- and SILAC-based untargeted proteomics
In this study, the effects of the contact allergens BQ, DNCB, NBB, Ni, and PPD were investigated in THP-1 cells. For this purpose, LFQ- and SILAC-based untargeted proteomics were applied.
ORGANISM(S): Homo sapiens (Human) 
2023-09-13 | PXD031017 | Pride
Silac Lfq Thp-1 Contact allergens 
ProteomicsProteomic characterization of calcium macrophages
In this study, macrophages, which differentiated from monocytes due to exposure to calcium and no further growth factors, were characterized. For this purpose, their proteomic profile was compared to monocytes, M1 macrophages, M2 macrophages, DCs, and foam cells obtained from healthy donors or patie...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD026888 | Pride
Human Macrophages Calcium Rheumatoid arthritis 
ProteomicsThe gut bacterium Extibacter muris produces secondary bile acids and influences liver physiology in gnotobiotic mice - Proteomics results
In this study, mice were colonized from birth on with the minimal microbiota Oligo-MM with or without the addition of Extibacter muris. Extibacter muris is known to metabolize cholic acid to deoxycholic acid via 7α-dehydroxylation. The impact of Extibacter muris colonization on the liver proteome of...
ORGANISM(S): Mus musculus (Mouse) 
2021-01-04 | PXD019973 | Pride
Mouse Tmt Liver Extibacter muris 
ProteomicsNanoToxClass: Investigation of dose- and time-dependent nanomaterial effects in alveolar epithelial cells
In this study, alveolar epithelial cells (cell line RLE-6TN) were treated with three different doses of nanomaterials (SiO2_15_Amino, SiO2_15_Unmod, SiO2_7, SiO2_40, TiO2_NM105) for 6 h, 24 h, and 48 h, respectively. The effects were investigated using untargeted proteomics.
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-29 | PXD020289 | Pride
Nanomaterials Rat Tmt Nanotoxclass Epithelial cells 
ProteomicsNanoToxClass: Investigation of dose-dependent nanomaterial effects in alveolar macrophages
In this study, alveolar macrophages (cell line NR8383) were treated with three different doses of nanomaterials (SiO2_15_Amino, SiO2_15_Unmod, SiO2_7, SiO2_40, TiO2_NM105) for 24 h. The effects were investigated using untargeted proteomics.
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-29 | PXD020158 | Pride
Macrophages Nanomaterials Rat Tmt Nanotoxclass 
ProteomicsNanoToxClass: Investigation of dose-dependent nanomaterial effects after short-term inhalation studies (STIS) with rats
In this study, rats were exposed to three different doses of nanomaterials (SiO2_7, TiO2_NM105) using short-term inhalations. Effects on exposure and recovery groups were compared using untargeted proteomics.
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-29 | PXD020178 | Pride
Nanomaterials Stis Rat Tmt Nanotoxclass 
ProteomicsNanoToxClass: Investigation of dose-dependent nanomaterial effects after instillations with rats
In this study, rats were exposed to three different doses of nanomaterials (SiO2_15_Amino, SiO2_15_Unmod, SiO2_7, SiO2_40) using instillations. Effects on exposure and recovery groups were compared using untargeted proteomics.
ORGANISM(S): Rattus norvegicus (Rat) 
2021-09-29 | PXD020184 | Pride
Instillation Nanomaterials Rat Tmt Nanotoxclass 
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