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ProteomicsBipolar and schizophrenia risk gene AKAP11 encodes an autophagy receptor coupling the regulation of PKA kinase network homeostasis to synaptic transmission
AKAP11 deficiency is associated with autophagy-regulated PKA and neuronal activity in mouse brains. We hypothesized that the differentially expressed proteins (DEPs) and phospho-proteins (pDEPs) in AKAP11 conditional KO mice and human iPSC-induced neurons (iNs) could be identified as potential AKAP1...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-12-08 | PXD067156 | Pride
Mouse models Synaptic transmission Er-resident autophagy-related proteins vapa/b Bipolar disorder (bd) Protein kinase a (pka) Pka-ri. Electrophysiology Akap11 Multi-omics Cell biology Schizophrenia (scz) Human induced neurons Gsk3a/b Sphkap 
UnknownA phase II study of ifosfamide, methotrexate, etoposide, and prednisolone for previously untreated stage I/II extranodal natural killer/T-cell lymphoma, nasal type: a multicenter trial of the Korean Cancer Study Group.
Not available
S-EPMC4221378 | biostudies-literature
UnknownPhospholipase Cγ1 links inflammation and tumorigenesis in colitis-associated cancer.
Not available
S-EPMC5814171 | biostudies-literature
ProteomicsP0 B6 mouse forebrain Ythdf2 LC-MS/MS
For P0 B6 mouse forebrain, to investigate the interacting protein partners with Ythdf2 with m6A, we compared the Mettl14 Nestin-Cre condition knockout mouse with WT mouse and changed the condition for IgG pulldown and Ythdf2 antibody pulldown.
ORGANISM(S): Mus musculus (Mouse) 
2026-09-14 | PXD080605 | Pride
Mouse Forebrain Ythdf2 Lc-ms/ms 
UnknownSREBP-2/PNPLA8 axis improves non-alcoholic fatty liver disease through activation of autophagy.
Not available
S-EPMC5073315 | biostudies-literature
UnknownPreferential Expression of Programmed Death Ligand 1 Protein in Tumor-Associated Macrophages and Its Potential Role in Immunotherapy for Hepatocellular Carcinoma.
Not available
S-EPMC8124544 | biostudies-literature
UnknownChemical Sensing Systems that Utilize Soft Electronics on Thin Elastomeric Substrates with Open Cellular Designs.
Not available
S-EPMC5630126 | biostudies-literature
UnknownTreat-to-target versus high-intensity statin treatment in patients with or without diabetes mellitus: a pre-specified analysis from the LODESTAR trial.
Not available
S-EPMC10520306 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
UnknownDrosophila muller f elements maintain a distinct set of genomic properties over 40 million years of evolution.
Not available
S-EPMC4426361 | biostudies-literature
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