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ProteomicsTWIST1 expression is associated with high-risk Neuroblastoma and promotes Primary and Metastatic Tumor Growth
In this study, merging in silico transcriptomic data and in situ TMA studies, we first highlighted the clinical significance and the value as prognostic factors of the embryonic TFs TWIST1 and TWIST2, thus linking their level of expression with the outcome of NB patients. Secondly, using NB cells k...
ORGANISM(S): Homo sapiens (Human) 
2022-01-10 | PXD024200 | Pride
Neuroblastoma Myofibroblasts Twist1/2 Tumor-stroma cross-talk Metastasis Tumor microenvironment Secretome Extracellular matrix 
ProteomicsEffect of epinephrine on a Micrococcus luteus biofilm matrix proteome
The importance of the impact of human hormones on commensal microbiota and microbial biofilms is established in lots of studies. In the present investigation, we studied the proteome of the biofilm matrix of the commensal actinobacterium Micrococcus luteus C01. In our investigation, we tested the ...
ORGANISM(S): Micrococcus luteus (Micrococcus lysodeikticus) 
2022-09-20 | PXD035739 | Pride
Lc-msms Micrococcus luteus Epinephrine 
ProteomicsType 2 diabetes risk gene Dusp8 is a gatekeeper for hypothalamic Jnk signaling and insulin sensitivity
Recent genome-wide association studies (GWAS) identified Dusp8, a dual-specificity phosphatase targeting MAP kinases, as type 2 diabetes risk gene. Here, we unravel Dusp8 as gatekeeper in the hypothalamic control of glucose homeostasis in mice and humans. Male but not female Dusp8 loss-of-function m...
ORGANISM(S): Mus musculus (Mouse) 
2020-08-17 | PXD019451 | Pride
Leptin Jnk Type2 diabetes Dusp8 
ProteomicsEffect of epinephrine on a proteome of Cutibacterium acnes
The importance of the impact of human hormones on commensal microbiota and microbial biofilms is established in lots of studies. In the present investigation, we studied the proteome of biofilms and planktonic cultures of skin actinobacterium Cutibacterium acnes. In our investigation, we tested the...
ORGANISM(S): Cutibacterium acnes subsp. defendens ATCC 11828 
2024-07-03 | PXD049410 | Pride
Lc-msms Cutibacterium acnes Epinephrine 
ProteomicsMitochondrial microproteins link metabolic cues to respiratory chain biogenesis
Electron transport chain (ETC) biogenesis is tightly coupled to energy levels and availability of ETC subunits. Coenzyme Q: cytochrome c oxidoreductase (complex III or CIII) occupies a central position in the ETC, receiving electrons from diverse fuel sources to control the ubiquinol:ubiquinone (CoQ...
ORGANISM(S): Mus musculus (Mouse) 
2022-09-25 | PXD030258 | Pride
Metabolism Sep Mitochondria Oxphos Micropeptides 
UnknownExtended pharmacological thromboprophylaxis and clinically relevant venous thromboembolism after major abdominal and pelvic surgery: international, prospective, propensity score-weighted cohort study.
Not available
S-EPMC11894929 | biostudies-literature
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