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ProteomicsLC-MSMS based Phosphoproteomics of BubR1
To identify phosphorylation sites on BubR1 that regulates its acetylation at lysine 250 (K250), LC-MSMS analysis was performed using HeLa cells expressing wild-type BubR1 (WT), an acetylation-deficient mutant (K250R), and an acetylation-mimetic mutant (K250Q).
ORGANISM(S): Homo sapiens (Human) 
2025-12-22 | PXD066850 | Pride
Bubr1 Hela Phosphorylation 
ProteomicsLC-MSMS analyses of purified, recombinant TcJHR complexes
Juvenile hormone (JH) serves vital roles in insect reproduction, development, and many aspects of physiology. JH primarily acts at the gene-regulatory level through an intracellular receptor. The JH receptor (JHR) is a ligand-activated complex of transcription factors of the bHLH-PAS family, consist...
ORGANISM(S): Tribolium castaneum (Red flour beetle) 
2022-02-16 | PXD028394 | Pride
Lc-msms Juvenile hormone receptor Tribolium castaneum 
ProteomicsHuman CRC cell line baseline phosphoproteomics
There is a need for robust phosphopeptide enrichment methods to allow signaling network analysis in cancer cell lines and tissues with minimal fractionation. With recent instrument developments thousands of unique phosphopeptides can be detected by single-shot LC-MS/MS. However, successful phosphopr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080788 | MassIVE
ProteomicsReproducibility of label-free single-shot phosphoproteomics applied to CRC cell lines
There is a need for robust phosphopeptide enrichment methods to allow signaling network analysis in cancer cell lines and tissues with minimal fractionation. With recent instrument developments thousands of unique phosphopeptides can be detected by single-shot LC-MS/MS. However, successful phosphopr...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-28 | MSV000080715 | MassIVE
ProteomicsTargeting kinome reprogramming in ESR1 fusion-driven breast cancer
Multiplexed, deep-scale LC-MSMS analysis for proteome and phosphoproteome expression profile and the targeted LC-MSMS analysis for kinases in enriched kinome of the ER+ breast cancer patient-derived xenograft tumors.
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2023-10-24 | PXD036644 | Pride
Lc-msms Esr1 fusion Breast cancer Breast cancer patient-derived xenograft (pdx) tumor Proteome Phosphoproteome 
ProteomicsMouse ESC LC-MSMS Ionising radiation
Dose-dependent (phospho) proteome responses of mouse embyronic stem cells to ionising radiation. Quantitative SILAC- and mass spectrometry-based proteomics and phosphoproteomics experiments were performe at half an hour (0.5h) and four hours (4h) after exposure to LD (0.1 Gy) and high doses (HD; 1 G...
ORGANISM(S): Mus musculus (Mouse) 
2022-03-18 | PXD025343 | Pride
Reactive oxygen species Transporter Phosphoproteome Ionising radiation Mouse Mitochondria Proteome Dna damage response 
ProteomicsFKH1 phosphoproteomics TMT LC-MS
Phosphoproteomics of FKH1 in comparison to U937 cells as negative control
ORGANISM(S): Homo sapiens (Human) 
2022-10-14 | PXD031429 | Pride
U937 Phosphoproteomics Fkh1 
ProteomicsSoybean, root-rhizobia, LC-MSMS
We previously found that rhizobia-inoculation enhanced the soybean's salt tolerance; the transcription factor (TF) GmMYB173 and its downstream gene GmCHS5 dictate soybean’s flavonoid metabolism in response to this stress. For revealing the mechanism of the enhancement, quantitative phosphoproteomics...
ORGANISM(S): Glycine max 
2019-09-02 | PXD006600 | Pride
Lc-msms Root-rhizobia Soybean 
ProteomicsMulti-level proteomics profiling of virus-restrictive and -permissive cellular environments reveal novel regulators of virus infection
Virus proliferation inside host cells relies on a diverse range of host machineries and is also restricted by the host through expressions of antiviral factors. The configuration of virus-dependency and antiviral factors determine the permissiveness of host cells to virus infection, however, overall...
ORGANISM(S): Homo sapiens (Human) 
2025-06-16 | PXD052223 | Pride
Human Innate immunity Lc-msms Hek293 cell line Proteomics Silac Phosphoproteomics Hek293t cell line 
ProteomicsPhosphoproteomics of yeast strains undergoing nitrogen or phosphate starvation
In the project «Phosphoproteomics of yeast strains undergoing nitrogen or phosphate starvation» phosphoproteomics and expression proteomics were performed. In biological triplicates label-free quantification of different S. cerevisiae strains was performed. Five strains were used:(a) Ctrl WT, (b) WT...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-12-15 | PXD045932 | Pride
Nitrogen Lc-msms Yeast Starvation Phosphate Phosphoproteomics 
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