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Newcastle disease (ND) is an acute, febrile, and highly contagious disease caused by the virulent Newcastle disease virus (vNDV) worldwide. The disease causes serious economic losses to the poultry industry. However, the metabolic changes caused by vNDV infection remain unclear. The objective of thi...
2019-12-20 | MTBLS1115 | MetaboLights
To explore the effect of hyperlipidemia on macrophages' innate immune response to Porphyromonas gingivalis invasion 12 samples, 3 replicates in 4 groups, with cells from hyperlipidemic ApoE deficient mice and nonhyperlipidemic C57BL/6 mice stimulate with or without P.gingivalis(Pg)
ORGANISM(S): Mus musculus 
Gastric cancer (GC) stem cells (GCSCs) are characterized as high level of ALDH activity, however, the mechanisms of maintenance of high ALDH activity and stemness in GCSCs are largely unknown. Here, we report that KDM4C, a H3K9me2/3-demethylase, epigenetically regulates ALDH1A3 by histone demethylat...
ORGANISM(S): Homo sapiens (Human) 
2022-02-16 | PXD023455 | Pride
We have investigated the proteome changes induced by SOX4 overexpression in HCT-116 cells using iTRAQ-based quantitative proteomics. Bioinformatics analysis revealed that HDAC1 could be one of the important regulators in cancer stem cells (CSCs) maintenance. We found that SOX4 transcriptionally regu...
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD019694 | Pride
The pathogenesis of endometriosis may result from aberrant angiogenesis that occurs in eutopic endometrium with retrograde menstruation. The difference in gene expression profile between human endometrial endothelial cells (HEECs) from eutopic endometria of patients with and without endometriosis wo...
ORGANISM(S): Homo sapiens 
H441 cell proteome was sequenced via SILAC and LC-MS/MS method to identify hypoxia-responsive proteins
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-05-15 | MSV000081087 | MassIVE
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