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UnknownChanges in Rumen Microbiota Affect Metabolites, Immune Responses and Antioxidant Enzyme Activities of Sheep under Cold Stimulation.
Not available
S-EPMC7999998 | biostudies-literature
ProteomicsAcetylome Profiling Reveals the Endogenous Substrates of HDAC6
HDAC6 inhibitors are novel targeted therapies showing good clinical response in a variety of different malignancies. However, their use and farther development is hampered by the limited knowledge regarding what are the endogenous substrates of HDAC6 enzyme. Here we plan to complete acetylome profil...
ORGANISM(S): Homo sapiens (Human) 
2022-11-09 | PXD026010 | Pride
Mass spectrometry Hap1 cell Acetylome Proteomics 
ProteomicsDUSP2 dephosphorylates STAT3 at Y705 and S727 residues
In the related study, to determine whether DUSP2 definitively served as a phosphatase for STAT3, an in vitro phosphatase assay was used. Using S-tag beads, p-STAT3 was pulled down from IL-6 stimulated HEK293T cells transfected with STAT3-S-Tag. DUSP2 or control protein, which was purified from HEK29...
ORGANISM(S): Homo sapiens (Human) 
2015-10-13 | PXD002743 | Pride
Dusp2 Phosphorylation Stat3 
ProteomicsWhole proteome and phosphoproteome profiling of CD8+ and CD8- dendritic cells
Analyzing and comparing proteome and phosphoproteome profiling between CD8+ DC and CD8- DC not only will be very helpful to understand the molecular mechanisms regulating CD8+/- DC differentiation and function but also can screen CD8+ or CD8- DC specific regulatory pathways or molecules.
ORGANISM(S): Mus musculus (Mouse) 
2018-06-11 | PXD006875 | Pride
Mass spectrometry Proteomics Phosphoproteomics Dendritic cells 
UnknownImplementing machine learning in bipolar diagnosis in China.
Not available
S-EPMC6861254 | biostudies-literature
UnknownEfficacy and safety of Epimedium total flavonoids for primary osteoporosis: a systematic review and meta-analysis.
Not available
S-EPMC11608984 | biostudies-literature
ProteomicsDeep Multilayer Brain Proteomics Identifies Molecular Networks in Alzheimer’s Disease Progression
The molecular networks underlying Alzheimer’s disease (AD) are not well-defined. We present temporal profiling of >14,000 proteins and >34,000 phosphosites at the asymptomatic and symptomatic stages of AD, deep proteomics analysis of transgenic mouse models.
ORGANISM(S): Mus musculus (Mouse) 
2020-04-16 | PXD018590 | Pride
Tmt-lc/lc-ms/ms Brain Ad mouse model 
UnknownInfluence of Macrocyclization Strategies on DNA-Encoded Cyclic Peptide Libraries.
Not available
S-EPMC12308377 | biostudies-literature
ProteomicsIdentification of RPA1 interactome in mouse liver tissue
To examine the molecular mechanisms by which RPA1 regulates transcription in liver, we conducted immunoprecipitation followed by mass spectrometry to characterize RPA1-associated proteins in mouse liver.
ORGANISM(S): Mus musculus (Mouse) 
2022-07-19 | PXD021529 | Pride
Mouse liver Rpa1 Interactome 
UnknownCovalent DNA-Encoded Library Workflow Drives Discovery of SARS-CoV-2 Nonstructural Protein Inhibitors.
Not available
S-EPMC11673110 | biostudies-literature
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