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ProteomicsGlobal and phospho-proteome of Hek293T treated with kinase inhibitors
We examine the changes in HEK293T overexpressing alpha-synucleinA53T-GFP when treated with kinase inhibitors (SB203580, GF109203X,SB202190, Enzastaurin, VX-745). Main findings is altered protein translation, with an increase in lysosomal proteins for all compounds save VX-745
ORGANISM(S): Homo sapiens (Human) 
2021-07-05 | PXD024508 | Pride
Lc-msms Enzastaurin Hek293t Alpha-synuclein Gf109203x Sb202190 Vx-745 Sb203580 
ProteomicsThe potential binding proteins of FOXQ1 were detected by mass spectrometry technology, laying the foundation for the subsequent in-depth study of its molecular mechanism
First, Flag-FOXQ1 was overexpressed in HCT-116 cells. Subsequently, the Flag-FOXQ1 complex was enriched via immunoprecipitation (IP) technology. The complex was then washed four times with phosphate-buffered saline (PBS), denatured in loading buffer by boiling, and separated via gel electrophoresis ...
ORGANISM(S): Homo Sapiens 
PXD064807 |
MetabolomicsPRDM15 is a master regulator of metabolism essential to sustain B-cell lymphomagenesis
PRDM family members are sequence-specific transcriptional regulators involved in cell identity and fate determination and are often dysregulated in cancer. The PRDM15 gene is of particular interest, given its relatively low expression in adult tissues and its overexpression in follicular lymphomas (...
2025-06-16 | MTBLS1639 | MetaboLights
UnknownObligate mutualism within a host drives the extreme specialization of a fig wasp genome.
Not available
S-EPMC4053974 | biostudies-literature
ProteomicsIntegrative proteomic characterization of human lung adenocarcinoma
Genomic studies of lung adenocarcinoma (LUAD) have advanced understanding of the disease’s biology and accelerated targeted therapy. However, proteomic characteristics of LUAD remain poorly understood. We carried out comprehensive proteomic analysis of 103 cases of LUAD in Chinese patients. Integrat...
ORGANISM(S): Homo Sapiens 
PXD020252 |
UnknownGenetically Determined Plasma Lipid Levels and Risk of Diabetic Retinopathy: A Mendelian Randomization Study.
Not available
S-EPMC5697951 | biostudies-literature
UnknownImpact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis.
Not available
S-EPMC5595282 | biostudies-literature
UnknownContinual Decline in Azole Susceptibility Rates in Candida tropicalis Over a 9-Year Period in China.
Not available
S-EPMC8299486 | biostudies-literature
UnknownPrognostic evaluation of quick sequential organ failure assessment score in ICU patients with sepsis across different income settings.
Not available
S-EPMC10804657 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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