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ProteomicsGIPC3 AP-MS/MS from chick inner ear extracts
To understand how GIPC3 exerts its effects on cuticular plate dimensions, we examined the GIPC3 protein-interaction network in hair cells. We immunoaffinity purified GIPC3 from crosslinked chicken inner ear extracts that were enriched for stereocilia, but still contain large amounts of hair-cell cyt...
ORGANISM(S): Gallus gallus (Chicken) 
2023-05-09 | PXD038234 | Pride
Stereocilia Myosin Cytoskeleton Hair cell Actin Hair bundle 
ProteomicsDiscovery of RSV-induced BRD4 protein interactions using native immunoprecipitation and parallel accumulation – serial fragmentation (PASEF) mass spectrometry
Respiratory Syncytial Virus (RSV) causes severe inflammation and airway pathology in children and the elderly by infecting the epithelial cells of the upper and lower respiratory tract. RSV replication is sensed by intracellular pattern recognition receptors upstream of the IRF and NF-$\upkappa$B tr...
ORGANISM(S): Homo sapiens (Human) 
2021-03-17 | PXD023983 | Pride
Human Ap-ms Brd4 Lung Rsv 
UnknownClinical outcomes in pediatric intestinal failure: a meta-analysis and meta-regression.
Not available
S-EPMC6669059 | biostudies-literature
ProteomicsProteomic Characterization of human small airway epithelial cells (hSAECs) in the context of respiratory syncytial virus infection and BRD4 inhibition.
Bromodomain-containing Protein 4 (BRD4) is a transcriptional regulator associated with cancer biology, inflammation, and fibrosis. In airway viral infection, non-toxic BRD4-specific inhibitors (BRD4i) block the release of pro- inflammatory cytokines and prevent downstream remodeling. Although the ch...
ORGANISM(S): Homo sapiens (Human) 
2023-06-13 | PXD039212 | Pride
Human Epithelial Lc-ms Airway Diapasef 
UnknownBrain PET Imaging of α7-nAChR with [18F]ASEM: Reproducibility, Occupancy, Receptor Density, and Changes in Schizophrenia.
Not available
S-EPMC6030963 | biostudies-literature
UnknownVelocity-Selective Arterial Spin Labeling Perfusion in Monitoring High Grade Gliomas Following Therapy: Clinical Feasibility at 1.5T and Comparison with Dynamic Susceptibility Contrast Perfusion.
Not available
S-EPMC10886779 | biostudies-literature
UnknownPalladium prompted on-demand cysteine chemistry for the synthesis of challenging and uniquely modified proteins.
Not available
S-EPMC6082840 | biostudies-literature
UnknownDynamic glucose-enhanced MRI of gliomas: A preliminary clinical application.
Not available
S-EPMC11604297 | biostudies-literature
ProteomicsLysine acetylation of chloroplast proteins 2
In photosynthesis, light is absorbed by the thylakoid embedded light harvesting pigment protein complexes (LHCs) that surround the photosynthetic reaction centers, photosystem II (PSII) and photosystem I (PSI). The distribution of light energy between the photosystems is balanced through state trans...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2018-07-03 | PXD007630 | Pride
Arabidopsis Lc-msms Plant 
ProteomicsQuantitative phosphoproteomic for CDKL5 substrates
Global phosphoproteomic screen to identify the first cellular substrates of CDKL5. CDKL5 knock-out U2OS cells and CDKL5 wt U2OS cells were generated for the TMT-based phosphoproteomic. Thi leads to the identification and further validation of several phosphopetides of MAP1S, CEP131 and CDKL5 itself....
ORGANISM(S): Homo sapiens (Human) 
2018-09-24 | PXD009374 | Pride
Cdkl5 substrates Phosphoproteomic Tmt Ms2 
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