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detection and qunatitation of proteins by mass spectromerty to see the effect of drug treatment in human cell lines.
ORGANISM(S): Homo sapiens (Human) 
2019-11-12 | PXD011721 | Pride
Molecular switches are essential modules in signaling networks by enabling a quick response to environmental changes. Here, we describe a role for small ubiquitin-like-modifier SUMO as a molecular switch in epidermal growth factor receptor (EGFR) signaling. Using quantitative mass spectrometry, we c...
ORGANISM(S): Homo sapiens (Human) 
2021-04-13 | PXD018049 | Pride
Comparison of MeroX in different modes and XlinkX upon variation of database size based on DSBU linked BSA as test-dataset
ORGANISM(S): Bos taurus (Bovine) 
2020-11-17 | PXD021648 | Pride
We aimed to find proteins associated with HNRNPH in bloodstream-form _Trypanosoma brucei_. We integrated a sequence encoding a cleavable TAP (Tandem Affinity Purification) tag into the genome upstream of, and in frame with, one _HNRNPH_ gene. The other allele was deleted. TAP-HNRNPH was purifed fro...
ORGANISM(S): Trypanosoma brucei 
2022-10-15 | PXD037289 | Pride
The SUMO protease SENP6 disassembles SUMO chains and thus SENP6 depletion should lead to the extension of SUMO polymers on substrates. We have used a proteomic method to identify putative SENP6 substrates based on increased apparent molecular weight after SENP6 depletion. This method uses SDS-PAGE f...
ORGANISM(S): Homo sapiens (Human) 
2024-03-01 | PXD036743 | Pride
human lung fibroblasts WT and ATG7KO (two clones) were used for unbiased SILAC/AHA-based secretome and proteome measurements.
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD025001 | Pride
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