Sort   by:  
 Page size 
GenomicsNext Generation Sequencing Facilitates Quantitative Analysis of Wild Type and MttpIKO liver Transcriptomes on methioine defcient diet (MCD)
Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and MttpIKO liver Transcriptomes on methioine defcient diet (MCD)
PRJNA754673 | ENA
UnknownSupramolecular Pd@methioine-EDTA-chitosan nanocomposite: an effective and recyclable bio-based and eco-friendly catalyst for the green Heck cross-coupling reaction under mild conditions.
Not available
S-EPMC10295217 | biostudies-literature
TranscriptomicsNext Generation Sequencing Facilitates Quantitative Analysis of Wild Type and MttpIKO liver Transcriptomes on methioine defcient diet (MCD)
Purpose: The goals of this study is to use NGS-derived liver transcriptome profiling (RNA-seq) to identify candidates of pathways and genes which are responsible to protect MttpIKO from MCD induced-NASH development .
ORGANISM(S): Mus musculus 
2021-10-20 | GSE182130 | GEO
ProteomicsProteome of CD4 T cells activated through the TCR in the presence of IL2 and IL12 - Part 1
To activate primary T cells, lymph nodes were removed and disaggregated. Cells were cultured in RPMI 1640 containing L-glutamine, 10% FBS, 50 μM β-mercaptoethanol and penicillin/streptomycin. Cells were stimulated with 1 μg/ml of the CD3 monoclonal antibody (2C11) and 2 μg/ml anti-CD28 (37.51) in t...
ORGANISM(S): Mus musculus (Mouse) 
2019-03-29 | PXD012052 | Pride
Metabolism Methioine Transport T cells 
ProteomicsImpact of Acute methionine restriction on proteome of Th1 cells - Part 2
CD4 T cells were activated using CD3/CD28 antibodies in the presence of IL2 and IL12, to generate Th1 cells. Th1 cells were maintained and expanded in IL2 and IL12, on D5 Th1 cells were sorted for CD4+ expression and DAP1 exclusion. After flow sorting, live TH1 cells were resuspended (1e6 per ml) in...
ORGANISM(S): Mus musculus (Mouse) 
2019-03-29 | PXD012053 | Pride
Metabolism Methioine Transport T cells 
ProteomicsInteractome analysis of human phospholipase D and phosphatidic acid-associated protein network
Using a systematic proteomic approach, we define the protein-protein interaction network for PLD superfamily and phosphatidic acid in human cells and reveal diverse cellular signaling events involved for this key protein family and lipid.
ORGANISM(S): Homo sapiens (Human) 
2022-01-16 | PXD029183 | Pride
Pja2 Sphk1 Phosphatidic acid S1p Phospholipase d Mtor 
ProteomicsA covalent fragment screen identifies ferroptosis induced by GPX4 inhibition as a vulnerability of senescent cells
Senescent cells drive ageing and age-related pathologies, including cancer. Consequently, senolytics, drugs that selectively kill senescent cells, have a broad therapeutic appeal. Here, we report a senolytic screen of a library of 10,480 covalent fragments. Amongst 44 identified hits, we found a ...
ORGANISM(S): Homo sapiens (Human) 
2026-02-23 | PXD068572 | Pride
Gpx4 Rsl3 Cancer Senescence Covalent fragments Ferroptosis Senolytics One-two punch Covalent inhibitors Chloroacetamides 
GenomicsMus musculus
SIRT1 regulates methionine metabolism and pluripotency of mouse embrynoic stem cells (mESCs)
PRJNA311351 | ENA
Sort   by:  
 Page size