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TranscriptomicsRegulation of myogenic progenitor proliferation in human fetal skeletal muscle by BMP4 and its antagonist Gremlin.
Analysis of the transcriptome of mononuclear side population (SP) and main population (MP) cells of human fetal skeletal muscle from 12 human subjects of gestational age 14-18 weeks. Total RNA was extracted and profiled from 12 human fetal skeletal muscle side population (SP) cells and 10 correspond...
ORGANISM(S): Homo sapiens 
2011-01-26 | E-GEOD-26869 | biostudies-arrayexpress
ProteomicsEffects of PGRMC1 phosphorylation status on MIA PaCa-2 cells
Progesterone Receptor Membrane Component 1 (PGRMC1) is expressed in many cancer cells, where it is associated with detrimental patient outcomes. Multiple different functions and cellular locations have been attributed to PGRMC1 in a variety of contexts, however the mechanisms underlying PGRMC1 biolo...
ORGANISM(S): Homo sapiens (Human) 
2020-03-03 | PXD014716 | Pride
Proteomics Swath Phosphorylation Pancreatic cancer 
ProteomicsPseudomonas aeruginosa proteome under hypoxic stress conditions mimicking the cystic fibrosis lung
Pseudomonas aeruginosa is a Gram-negative, opportunistic bacterium and a major etiological agent in monogenic disease cystic fibrosis (CF). High density colonies of P. aeruginosa are often isolated from hypoxic mucus plugs in respiratory tract of CF patients, indicating high adaptive capacities of t...
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2017-08-29 | PXD007233 | Pride
Cystic fibrosis Hypoxia Pseudomonas aeruginosa Tmt-ms Swath-ms 
UnknownPreparing Clinicians for Transitioning Patients Across Care Settings and Into the Home Through Simulation.
Not available
S-EPMC6042971 | biostudies-literature
ProteomicsChronic polypharmacy, monotherapy, and deprescribing: Understanding complex effects on the hepatic proteome of aging mice
Polypharmacy (use of 5 or more concurrent medications) is highly prevalent among older adults to manage chronic diseases and is linked to adverse geriatric outcomes, including physical and cognitive functional impairments, falls, frailty, hospitalization, and mortality. Deprescribing (withdrawal) i...
ORGANISM(S): Mus musculus (Mouse) 
2024-11-12 | PXD049469 | Pride
Aging Deprescribing Citalopram Mouse Simvastatin Oxybutynin Metoprolol Polypharmacy Dia Drug response Lc-ms Oxycodone Liver 
ProteomicsProteomic response to PhiX174 infection
Elucidating host-bacteriophage dynamics is an important approach to elucidating bacterial survival functions and responses to infection. The model bacteriophage φX174 endemically found amongst the human intestinal microbiota and has a long history of use in bacteriophage based research, however the ...
ORGANISM(S): Escherichia coli 
2021-04-08 | PXD021681 | Pride
Omics E. coli Bacteriophage 
ProteomicsPrognostic biomarkers of distant recurrence following curative-intent resection of early-stage rectal cancers
Curative-intent surgery is the recommended treatment for node-negative, early-stage rectal cancer. There is limited understanding of tumour biology linked to the infrequent events of distant recurrence in early-stage rectal cancer. The aim of this pilot study was to identify putative prognostic biom...
ORGANISM(S): Homo sapiens (Human) 
2026-09-07 | PXD071180 | Pride
Distant metastasis Lcms Human Rectal cancer 
ProteomicsProteomics of thyroid tumours - Proteomics of thyroid tumours provides new insights into their molecular composition and changes associated with malignancy
Although most thyroid tumours are benign, thyroid cancer represents the most common malignancy of the endocrine system, comprising mainly follicular and papillary thyroid carcinomas (FTC and PTC, respectively). Previous studies have shed some light on the molecular pathogenesis of thyroid cancer but...
ORGANISM(S): Homo sapiens (Human) 
2017-05-03 | PXD002732 | Pride
Swath Thyroid cancer proteomics 
ProteomicsRespiratory complex II - Alternative assembly of respiratory complex II connects energy stress to metabolic checkpoints
Alternative assembly of respiratory complex II connects energy stress to metabolic checkpoints
ORGANISM(S): Homo sapiens (Human) 
2018-10-18 | PXD009656 | Pride
Mitochondria  sdha  energy utilization 
ProteomicsCompare total proteomics profile of PaCa-2 cells using 1D and 2D IDA LC and SWATH analysis
Progesterone Receptor Membrane Component 1 (PGRMC1) is expressed in many cancer cells, where it is associated with detrimental patient outcomes. Multiple different functions and cellular locations have been attributed to PGRMC1 in a variety of contexts, however the mechanisms underlying PGRMC1 biolo...
ORGANISM(S): Homo sapiens (Human) 
2020-03-03 | PXD014789 | Pride
Cancer Proteomics Swath 
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